2-氯甲基呋喃与三烷基炔基硼酸盐的反应研究  

The Study on the Reaction,of 2-(Chloromethyl)furan with Lithium Trialkylalkynylborates

作　　者：李南生[1] 陈燕[1] 邓敏智[1] 马益林 

机构地区：[1]中国科学院上海有机化学研究所,上海200032

出　　处：《有机化学》1991年第3期322-325,共4页Chinese Journal of Organic Chemistry

摘　　要：近几年来,有机硼酸盐的化学是一个非常活跃的研究领域,三烷基炔基硼酸盐能与许多亲电试剂进行立体选择性的反应,经质子解,得到各种各样的三取代烯烃,其一般反应式如方程式(1)。在这些亲电试剂中,有的亲电试剂如:溴丙烯、溴苄、溴代丙酮。The reaction of 2-(chloromethyl)furan with lithium trialkylalkynylborate is stu-died and the configuration of the major reaction products is determined to be E-form by us-ing ~1H NMR NOE technique.The data of g.l.c.and ~1H NMR of the products indicate theratio of E and Z isomers of the products is about 80∶20.Thus the reaction with high stc-reoselectivity might be useful for the preparation of furan derivatives.

关 键 词：有机硼酸盐 氯甲基呋喃 反应 

分 类 号：O626.11[理学—有机化学]