二维接力HOHAHA和—维多重接力COSY研究苷类化合物的结构  

Structure Determination and Spectral Assignment of Glycoside by 2 D RELAY-HOHAHA Spectroscopy and 1 D multiple Relay COSY

作　　者：缪振春[1] 冯锐[1] 

机构地区：[1]军事医学科学院核磁共振实验室,北京100850

出　　处：《有机化学》1991年第5期517-522,共6页Chinese Journal of Organic Chemistry

摘　　要：苷类化合物的糖体质子大多相互有自旋偶合作用,构成一个复杂的自旋系统。糖体端基质子(H-1)NMR 信号大多为双峰。A two-dimensional RELAY-HOHAHA method and a 1 D relay multiple COSY method were developed.The results obtained showed that the efficiency of magnetization transfer in the sugar residue of glycoside is much better for these methods than that forconventional 2D HOHAHA and that for 2D four relay COSY.The subspectra correspon-ding to individual sugar components were extracted even from overlapping proton resonanceby taking the cross seetions of 2 D spectra parallel to the F 2 axis at anomeric proton reso-nance.Detained assigment of severe overlapping 1~H NMR spectra of sugar residues in glyco-side were achived by a combined use of 2 D RELAY-HOHAHA and 1 D multiple relayCOSY.

关 键 词：苷类化合物 结构 测定 NMR 

分 类 号：O629.13[理学—有机化学]