尿螨病的临床症状分析  

THE ANALYSIS OF CLINICAL SYMPTOM ON URINARY ACARIASIS

作　　者：李朝品[1] 王健[1] 

机构地区：[1]淮南工业学院医学分院,安徽淮南232001

出　　处：《中国寄生虫病防治杂志》2002年第3期183-185,共3页Chinese Journal of Parasitic Disease Control

基　　金：安徽省 1 997年高等学校自然科学资助项目 (No.97JW0 88)

摘　　要：目的　探讨尿螨病的临床症状 ,为诊治尿螨病提供依据。　方法　对 6 9例尿螨病患者进行尿常规检查、血常规检查、血清总 Ig E、螨特异性 Ig E检测、皮肤挑刺试验 ;对 11例尿螨病患者进行膀胱镜检查。　结果　尿螨病患者的主要临床症状为夜间遗尿和尿频、尿急、尿痛等尿路刺激症状 ,其次为颜面和 /或下肢水肿、尿量异常、蛋白尿、大量上皮细胞尿等。白细胞计数为 5 .3× 10 9/L～ 11.4× 10 9/L ,多数患者白细胞分类中的嗜酸性粒细胞有不同程度的增高 ,一般为 0 .0 5～0 .0 9之间 ,最高达 0 .4 8;嗜酸性粒细胞计数多在 0 .5× 10 9/L～ 0 .14× 10 9/L。尿螨阳性患者血清总 Ig E、螨特异性 Ig E水平明显高于尿螨阴性者 ,差异有显著性 (P<0 .0 1,P<0 .0 5 )。皮肤挑刺试验结果显示 ,“ ”者 4 9例 ,“+”者 2 0例。11例患者膀胱镜检查发现 ,膀胱三角区粘膜上皮增生、肥厚 ,固有膜内有浆细胞、淋巴细胞浸润 ,有聚集的粉红色脓肿 ,膀胱内壁轻度小梁性改变 ,侧壁局部呈充血样改变 ,毛细血管充血扩张。　结论　尿螨病的临床症状虽与泌尿系统其他疾病有雷同之处 ,但仍有诊断依据可循 ,如尿螨阳性 ,血清总 Ig E、螨特异性 IgObjective To probe the clinical symptom of urinary acariasis so as to provide the evidence to early diagnosis of urinary acariasis. Methods The routine urine examination, routine blood examination, total IgE, specific IgE of mites in serum, dermal sensitivity test were detected for the 69 patients with urinary acariasis that had been identified with the investigation of epidemiology. The test of cystoscopy was taken for the 11 patients with urinary acariasis. Results The main clinical manifestations were irritation sign of bladder (such as enuresis in the night, frequency of micturition, urgency of urination, urodynia) hydrops of face and lower limb, abnormality of urine volume, proteinuria, large epithelial cells in urine and so on. The leukocyte count was in the range from 5.3 ×10 9/L to 11.4×10 9/L. The eosinophilic granulogyte count was high in the classification of leukocytes and was in the range from 0.5 ×10 9/L to 0.14×10 9/L (normal 0.05~0.09, the highest 0.48). The levels of total IgE and specific IgE of acarida mites were higher in the positive patients than those in negative patients( P <0.01, P <0.05). The results of dermal sensitivity test showed that the positive number of '','+' were 49, 20 respectively. The tests of cystoscopy for 11 patients showed that the epithelium mucosae cells were active proliferation, pachynsis in trigone of urinary bladder, plasmocyte and lymphocytic infiltration and pink abscess in membrane propria, the change of trabecularism and congestion and telangiectasis in inter wall of bladder. Conclusions Urinary acariasis was deficient in specific clinical symptom. The characteristic clinical manifestations of urinary acariasis were positive of mites in urine, high level of total of IgE, specific IgE of acarida mites in serum, positive of dermal sensitivity test.

关 键 词：螨感染 尿螨病 分析研究 临床 

分 类 号：R384.4[医药卫生—医学寄生虫学]