击倒抗性和钠离子通道  

Knockdown resistance and sodium channel

作　　者：王建军[1] 韩召军[1] 王荫长[1] 

机构地区：[1]南京农业大学植物保护系

出　　处：《昆虫学报》2002年第3期391-396,共6页Acta Entomologica Sinica

基　　金：973国家重点基础研究项目 (J2 0 0 0 16 2 0 7) ;江苏省 95重点攻关课题 (BE96 370 )

摘　　要：综述了击倒抗性与钠离子通道关系的研究进展。毒理学和电生理学的研究表明 ,在许多拟除虫菊酯类杀虫剂抗性昆虫中存在击倒抗性。分子遗传学研究进一步发现 ,击倒抗性与钠离子通道位点连锁。最近的研究表明 ,昆虫神经系统对拟除虫菊酯类杀虫剂敏感性下降的击倒抗性机制是钠离子通道结构基因突变。但仍有一些问题 ,如突变的保守性和分布 ,需要进一步研究、阐明。This paper reviews the current progress of the relationship between Kdr - type resistance and sodium channel. Toxicological and electrophysiological studies have demonstrated the presence of Kdr -type resistance in many pyrethroid-resistant insects. Molecular genetic evidence has been presented that Kdr -type resistance is linked to a sodium channel locus in many pyrethroid-resistant insects. Moreover, a number of recent studies have already demonstrated that several mutations in structure gene of sodium channel are associated with Kdr -type resistance, which is thought to be the mechanism of reduced sensitivity of the insect nervous system to pyrethroid insecticides. However, several problems, such as the conservation and distribution of point mutation, remain to be clarified.

关 键 词：昆虫神经系统 拟除虫菊酯类杀虫剂 击倒抗性 钠离子通道 

分 类 号：Q965[生物学—昆虫学]