我国地方性氟中毒病区环境氟的安全阈值  

Safety Threshold of Fluorine in Endemic Fluorosis Regions in China

作　　者：李永华[1] 王五一[1] 侯少范[1] 

机构地区：[1]中国科学院地理科学与资源研究所,北京100101

出　　处：《环境科学》2002年第4期118-122,共5页Environmental Science

基　　金：国家自然科学基金项目 (40 1710 0 6 );中国科学院创新基金资助项目 (编号CXIOG A0 0 0 1)

摘　　要：概述了我国地方性氟中毒的 4个流行区域及其环境特征 ,揭示地方性氟中毒的流行与地球化学环境密切相关 ,研究了不同氟中毒病区氟从外环境到人体的传输途径及其剂量 效应关系 .选择氟斑牙检出率 5 %作为病区划分标准 ,确定了不同病区环境氟的安全阈值 。Four endemic fluorosis regions in China and their environmental epidemiological characteristics were summarized in this paper. It shows that the epidemiology of endemic fluorosis is closely related to geochemica parameters of local environment. The food web and dose effect relationship of fluoride from environment to human body in different types of endemic fluorosis regions were studied. And the safety threshold of fluoride in different regions was determined. The results have provided a scientific basis for environmental risk assessment of fluoride in China.

关 键 词：氟中毒 区域分异 剂量-效应 安全阈值 环境风险评价 中国 地方病 环境毒理学 

分 类 号：R599[医药卫生—内科学] R994.6[医药卫生—临床医学]