经皮肝穿射频治疗肝癌的临床研究  

A CLINICAL RESEARCH INTO RADIOFREQUENCY ABLATION IN TREATING LIVER CANCER THROUGH PERCUTANEOUS LIVER CENTESIS

作　　者：朱一宁[1] 阎文[1] 庞志东[1] 刘江泽[1] 

机构地区：[1]广西玉林市第一人民医院,玉林537000

出　　处：《肝胆外科杂志》2002年第3期178-180,共3页Journal of Hepatobiliary Surgery

摘　　要：目的　探讨经皮肝穿集束电极射频治疗肝癌的价值及适应证。方法　在 B超、CT、腹腔镜等引导下 ,使用RF2 0 0 0射频仪 ,对 38例肝癌患者共 4 6个结节进行集束电极射频治疗。比较治疗前后肝功能、AFP、瘤体血供及大小的变化。结果　术后 7d肝功能恢复正常 ,6 9.2 %的 AFP阳性病例术后 7d即出现 AFP下降 ,其中 4 2 .3%术后 30 d降至正常范围 (P<0 .0 5 )。彩色 B超及 CT复查显示 ,瘤体直径 <5 cm者 ,其术后 1～ 6月内瘤体血供消失 ,体积缩小甚至消失。瘤体直径≥ 5cm者 ,术后 1～ 6月内部分病例瘤体血供减少、体积缩小。结论　经皮肝穿集束电极射频治疗肝癌疗效确切。Objective To provide a research into the values and indications of radiofrequency ablation in treating liver cancer through percutaneous liver centesis.Methods A RF2000 is used,under the guidance of a Bus.CT and laparoscope,in radiofrequency ablation in the treatment of 46 tubercles in 38 patients with liver cancer.A comparison is carried out between the changes in liver function?AFP and the size and blood supply of neoplasm before and after the procedure.Results Seven days after the operation,liver function can return to normal.AFP is found to decrease one week after the operations for 69.2% patients whose AFP is positive;and thirty days after the operation,AFP is found to decrease to normal for 43.2% of them.Examine through colour US and CT show that blood supply of neoplasm disappears and the volume of neoplasm shrinks or even disappears,form one to six months after operations,for those patients whose neoplasm diameter is <5 cm.As for the patients whose neoplasm diameter is ≥5 cm,blood supply of neoplasm decreases and neoplasm volume shrinks in some cases from one to six months after operations.Conclusion Radiofrequency ablation through percutaneous liver centesis is a simple,safe and effective in the treatment of liver cancer.

关 键 词：肝肿瘤 介入性 集束电极 射频治疗 

分 类 号：R657.3[医药卫生—外科学]