乙肝病毒特异性转移因子治疗慢性乙型肝炎的临床研究  

A study on HBV-specific transfer factor in the treatment of chronic hepatitis B.

作　　者：黄文琪[1] 宋闽宁[1] 洪党阳[1] 夏挺[1] 骆梅兰[1] 周海波[1] 

机构地区：[1]解放军第174医院,厦门361003

出　　处：《中国实用内科杂志》2002年第7期397-398,共2页Chinese Journal of Practical Internal Medicine

摘　　要：目的　评价乙肝病毒特异性转移因子治疗慢性乙型肝炎的临床疗效。方法　选择慢性乙型肝炎 86例 ,随机分为两组。对照组 40例 ,应用常规保肝降酶疗法 ;研究组 46例 ,在保肝降酶疗法的基础上加用乙肝病毒特异性转移因子。结果　研究组HBeAg及HBVDNA的阴转率显著高于对照组 (P <0 0 5 ) ,抗 HBe阳转率亦显著高于对照组 (P <0 0 1)。结论　乙肝病毒特异性转移因子用于治疗慢性乙型肝炎 ,可以改善患者的乙肝病毒病原学指标。Objective To evaluate the efficacy of HBV-specific transfer factor in treatment of chronic hepatitis B.Methods 86 patients with chronic hepatitis B were randomly divided into two groups.40 patients of control group received routine treatment of protecting hepatocytes and dropping ALT levels,46 patients of study group received routine treatment with HBV-specific transfer factor.Results The negative rates of HBeAg and HBV DNA in study group were both significantly higher than those in control group(P<0^05).The rate of anti-HBe becoming postitive in study group was significantly higher than that in control group(P<0^01).Conclusion These results suggest that HBV-specific transfer factor may be beneficial in treatment of chronic hepatitis B.

关 键 词：乙肝病毒特异性转移因子 治疗 慢性乙型肝炎 临床分析 

分 类 号：R512.62[医药卫生—内科学]