消斑愈肾颗粒剂对大鼠IgA肾病免疫调节的研究  

The Experimental Study of Xiaobanyushen Granule Immunoregulation on Treating Experimental Iga Nephropathy Rats

作　　者：张君[1] 姜欣[1] 王莉[1] 郑学民[1] 

机构地区：[1]辽宁中医学院附属医院,辽宁大连110032

出　　处：《中国实验方剂学杂志》2002年第4期37-38,共2页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的 :观察消斑愈肾颗粒剂对大鼠实验性IgA肾病免疫调节作用。方法 :采用牛血清白蛋白和葡萄球菌肠毒素复合免疫法建立大鼠实验性IgA肾病模型 ,检测红细胞C3b受体花环 ,CH5 0 ,血清中IgGIgA含量。结果 :提示消斑愈肾颗粒剂对实验性大鼠IgA肾病RBC C3b受体功能下降及IgA升高均有调节作用 ,与对照组比较P <0 0 1。To study the effect of xiaobangyushen granule immunoregulation on treating experimental IgA nephropathy rats induced by feeding Bovine Serum Albumin(BSA)and injectciting staphylococcal Enter toxin B(SEB),rats were randomly divided into five groups.Results indicated xiaobangyushen granule showed obvious effects on the hypofunction of erythrocyte c3b receptor and the elevation of IgA on treating experimental IgA nephropathy rat's corn pared with that of controls( P <0 01)

关 键 词：免疫调节 消斑愈肾颗粒剂 IGA肾病 动物模型 

分 类 号：R285.5[医药卫生—中药学] R277.5[医药卫生—中医学]