飞行员脂肪负荷餐后红细胞聚集性变化的动态分析  

Dynamic observation of erythrocyte aggregation after a butter loading meal in pilots

作　　者：刘爱兵[1] 王丽珍[1] 苍中齐[1] 张书海[1] 

机构地区：[1]中国人民解放军第466医院,北京100089

出　　处：《中华航空航天医学杂志》2002年第2期81-83,共3页Chinese Journal of Aerospace Medicine

基　　金：空军医药卫生"十五"重点研究项目 (KW0 1Z2 0)

摘　　要：目的　观察脂肪负荷餐后富含甘油三酯的脂蛋白 (TRL)和红细胞聚集性的动态变化。　方法　 5 0名飞行员分为试验组和对照组 ,每组 2 5人 ,试验组在定量进食早餐的基础上加服脂肪负荷餐 ;对照组仅定量进食早餐。空腹及餐后 3和 8h各测定甘油三酯 (TG)和高密度脂蛋白 -胆固醇(HDL- C)水平 ,同时测定 4项红细胞参数和 4项红细胞聚集参数。　结果　与空腹水平相比 ,试验组餐后 3h TG升高、HDL- C降低 (P<0 .0 1)。餐后 8h TG恢复至空腹水平 (P>0 .0 5 ) ,但 HDL- C未升至空腹水平 (P<0 .0 1)。与空腹测定值相比 ,试验组餐后 3和 8h红细胞比容和 4项红细胞聚集参数增高 (P<0 .0 1或 P<0 .0 5 )。对照组空腹、餐后 3和 8h上述指标差异无显著性意义 (P>0 .0 5 )。　结论　脂肪负荷餐后在高 TG/低 HDL- C血症的同时 ,存在红细胞聚集力增强 ,延续时间更长。Objective To observe the dynamic change of plasma triglyceride(TG) and high density lipoprotein cholesterol(HDL C) levels and erythrocyte aggregation after a butter loading meal in pilots. Methods Fifty fighter pilots aged 22~24 served as subjects. They were randomly divided into 2 groups: experimental and control. A rationed breakfast was given to all of them, and for experimentals butter in a dosage of 1.3 g/kg body weight was added. Blood samples were collected in the morning, 3 h and 8 h after meal for measuring plasma TG, HDL C levels, erythrocyte indexes and erythrocyte aggregation parameters. Results Compared with the fasting level, there were no significant change of TG level 3 h and 8 h after meal in control group, while in experimental group significant increase of TG was found 3 h after meal but the increase became non significant at 8 h after meal. No significant changes of hematocrit (HCT) and parameters of erythrocyte aggregation were found 3 h and 8 h after meal in control group, while in experimental group, HCT and parameters of erythrocyte aggregation were increased significantly both at 3 h after meal and 8 h after meal. Conclusion Viewing that a butter loading meal can induce not only elevating of TG and lowering of HDL C level, but also significant change of HCT and RBC aggregation index, the dietary control of pilots should be taken.

关 键 词：飞行员 脂肪负荷餐后 红细胞聚集 动态分析 动脉粥样硬化 脂肪耐量试验 

分 类 号：R85[医药卫生—航空、航天与航海医学]