电刺激中脑导水管周围灰质对猫丘脑后核内脏大神经诱发放电的影响  

EFFECTS OF STMULATING PERIAQUEDUCTAL GRAY ON THE NOCICEPTIVE NEURON DISCHARGES OF PO NUCLEUS EVOKED BY STIMULATION OF SPLANCHNIC NERVE IN CATS

作　　者：张瑞德[1] 蔡奎[1] 那杰[2] 马晓玲[1] 刘淑珍[1] 王欢[1] 滕国玺[1] 

机构地区：[1]中国医科大学脑研究所 [2]沈阳师范学院生理教研室

出　　处：《针刺研究》1991年第1期10-14,共5页Acupuncture Research

摘　　要：国内外的工作表明中脑导水管周围灰质(Pariagueauctal grag,简称PAG)是与镇痛作用密切相关的神经结构,也是微量注射吗啡和电刺激可产生最有效镇痛作用的脑区。此部位阿片受体较为密集。The effects of stimulating periaqueductal gray (PAG) on the nociceptive neuron discharges of ponucleus evoked dy stimulating the splanchnic nerve in cats were studied. The two kinds of inhibitory action were observed. One was called early phase or prompt inhibition phase which occured within 30 ms to 150 ms after stimulation of PAG. The other was called slow-pase or sustained inhibition which occured from a few minutes to more than ten minutes after the stimulation of PAG. The results showed that PAG played an important role in the analgesia of visceral rain. Both kinds of inhibition may be blocked by naloxone, this suggests that endogencus opiate like substances involved in these inhibitory processes caused by stimulating role in the inhibitory effect of PAG.

关 键 词：电剌激 中脑导水管 周围灰质 猫 

分 类 号：R245.97[医药卫生—针灸推拿学]