腹膜透析相关性真菌性腹膜炎易感因素及预后分析  

Analysis of risk factors and prognosis of peritoneal dialysis-related fungal peritonitis

作　　者：赵洪静[1] 许坤[1] 吴永贵[1] 

机构地区：[1]安徽医科大学第一附属医院肾脏内科,合肥230022

出　　处：《安徽医学》2015年第1期26-29,共4页Anhui Medical Journal

基　　金：教育部博士点基金(20093420110003)

摘　　要：目的探讨腹透相关性真菌性腹膜炎(FP)易感因素及预后。方法回顾性分析20例次FP临床资料,与同期收治的腹透相关性细菌性腹膜炎(BP)比较,分析FP的易感因素及预后。结果腹透相关性腹膜炎共400例次,FP占5.0%;FP组血红蛋白低于BP组;FP组中,45%患者近1个月内有腹腔或全身使用抗菌药物史,高于BP组(15%)。20例次FP中1例治愈,15例拔管,4例自动出院。FP组腹膜透析退出率及患者病死率均明显高于BP组。结论严重贫血,腹腔或全身使用抗菌药物是FP发生的高危因素,FP预后不良,尽早拔管可能降低病死率。Objective To investigate the risk factors and outcomes of peritoneal dialysis related fungal peritonitis( FP). Methods FP episodes in 2008 ~ 2013 in our hospital were retrospectively reviewed. The clinical characteristics and outcomes were compared with those of bacterial peritonitis( BP) in the same period. Results In the 400 peritonitis reviewed,FP accounted for 5. 0%. The hemoglobin in FP was significantly lower than that in BP. 45% of FP episodes had a history of antibiotic use within one month,which was significantly higher than that in BP. Among the 20 FP patients,1 was cured,15 removed the catheter,4 were discharged without cure. The mortality and the dropping out rate of PD in FP were significantly higher than those in BP. Conclusion Severe anemia and the use of antibiotics within 1 month are the risk factors of FP. FP will lead to high mortality and dropping out rate of PD. Early catheter removal can decrease the mortality of FP.

关 键 词：腹膜透析 真菌性腹膜炎 易感因素 预后 

分 类 号：R473.5[医药卫生—护理学]