超声热疗技术的发展与应用  

Development and Application of Ultrasound Technology for Hyperthermia

作　　者：翟 亮[1] 孙福成[1] 蒋继伟[1] 萧翔麟[1] 钱晓平[1] 王一抗 俞仁康[1] 徐勇江[1] 张洪峰[1] 

机构地区：[1]上海交通大学生物医学工程系,上海200030

出　　处：《中国医疗器械杂志》2002年第4期281-283,280,共4页Chinese Journal of Medical Instrumentation

摘　　要：超声热疗很早就被用于治疗癌症及良性肿瘤,生物学实验和临床表明:41℃-45℃的热疗能显著增强放疗和化疗的疗效,而高于65℃的高温热疗可以代替传统的介入式疗法来摧毁肿瘤组织,使肿瘤组织凝固、坏死、脱落。高强度聚焦超声（HIFU）能在短时间内使癌变组织的温度升至65℃以上,导致病变组织凝固、坏死。高强度聚焦超声作为一种具有巨大潜力的、无损的、有效的局部治疗手段,受到普遍关注。目前,中国在高强度聚焦超声临床上已处于世界领先水平。文中介绍了超声热疗技术的发展和应用。It has been a long time since ultrasound hyperthermia began to be used in the clinical management of cancers and benign diseases.Numerous biological and clinical investigations have demonstrated that: hyperthermia in the range of 41-45℃ can significantly enhance clinical response to radiation therapy and chemotherapy, and high-temperature hyperthermia(greater than 65℃)alone is now being used as an alternative to conventional invasive surgery for selective tissue destruction, causing tumor coagulation and necrosis. As a promising noninvasive and effective local therapy, HIFU has attracted great attention. China is advanced in the clinical applications of HI-FU.This article gives an introduction of the development and applications of ultrasound hyperthermia technology, and also provides a general review of a selection of ultrasound hyperthermia systems both in clinical use and under development.

关 键 词：超声热疗 多元阵探头 高强度聚焦超声 HIFU 肿瘤 

分 类 号：R454.5[医药卫生—治疗学] R730.5[医药卫生—临床医学]