Synthesis,Crystal Structure and Absolute Configuration of (+)-(a-Hydroxybenzyl)phenylphosphinic acid  

作　　者：蔡觉晓 周正洪 唐除痴 王宏根 

机构地区：[1]State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry,Nankai University, Tianjin 300071, China [2]Central Laboratory, Nankai University, Tianjin 300071, China

出　　处：《Chinese Journal of Structural Chemistry》2002年第4期368-370,共3页结构化学（英文）

基　　金：Financial support by the National Natural Science Foundation of China (No.29872016)

摘　　要：The title compound (+)-(a-hydroxybenzyl)phenylphosphinic acid (C13H13O3P, Mr = 248.20) has been synthesized and characterized by 31P NMR, 1H NMR and elemental analysis. X-ray diffraction analysis at 293(2) K indicates that the compound belongs to monoclinic system, space group C2 with cell parameters: a = 23.560(8), b = 6.947(2), c = 7.854(3) ? b = 91.273(6)? V = 1285.2(7) 3, Z = 4, Dc = 1.283 g/cm3, F(000) = 520 and m(MoKa) = 0.207 mm-1. The number of independent reflections amounts to 1991, of which 1507 are observed reflections. The crystal structure has been determined by direct methods (SHELXL-97). The structure parameters are refined by full-matrix least-squares on F2 to R = 0.0437 and wR = 0.0893. The flack x parameter is 0.0001. The absolute configuration of the a-carbon in the title compound is S.

关 键 词：a-hydroxyphosphinic acid (+)-(a-hydroxybenzyl)phenylphosphinic acid crystal structure absolute configuration 

分 类 号：O627.51[理学—有机化学]