3-甲基-1-磺酸咪唑硫酸氢盐催化剂用于四组分一锅法合成不对称聚羟基喹啉衍生物(英文)  

Four-component one-pot synthesis of unsymmetrical polyhydroquinoline derivatives using 3-methyl-1-sulfonic acid imidazolium hydrogen sulfate as a catalyst

作　　者：Nader Ghaffari Khaligh 

机构地区：[1]Department of Chemistry,Qaemshahr Branch,Islamic Azad University,Qaemshahr,47651-61964,Iran [2]Research House of Professor Reza,Education Guilan District 1,Rasht,41569-17139,Iran

出　　处：《催化学报》2014年第7期1036-1042,共7页

摘　　要：3-Methyl-1-sulfonic acid imidazolium hydrogen sulfate has been used as an efficient, halogen-free,and reusable Brnsted acidic ionic liquid catalyst for the synthesis of ethyl-4-aryl/heteryl- hexahydro-trimehtyl-5-oxoquinoline-3-carboxylates via the one-pot condensation of dimedone with aryl/heteryl aldehydes, ethyl acetoacetate, and ammonium acetate under solvent-free conditions. This method has the advantage of being clean and simple, as well as providing the desired product in high yield over a short reaction time. Furthermore, the catalyst could be recycled and reused four times without any discernible reduction in activity.3-Methyl-1-sulfonic acid imidazolium hydrogen sulfate has been used as an efficient, halogen-free, and reusable Bronsted acidic ionic liquid catalyst for the synthesis of ethyl-4-aryl/heteryl- hexahy-dro-trimehtyl-5-oxoquinoline-3-carboxylates via the one-pot condensation of dimedone with aryl/heteryl aldehydes, ethyl acetoacetate, and ammonium acetate under solvent-free conditions. This method has the advantage of being clean and simple, as well as providing the desired product in high yield over a short reaction time. Furthermore, the catalyst could be recycled and reused four times without any discernible reduction in activity.

关 键 词：离子液体催化剂 一锅合成 硫酸氢 咪唑 磺酸 四组分 衍生物 不对称 

分 类 号：O643.36[理学—物理化学] O631.5[理学—化学]