湿热瘀阻与活动期类风湿关节炎骨侵蚀  

Damp-Heat Stasis Obstruction and Bone Erosion in Active Rheumatoid Arthritis: A Theoretical Exploration

作　　者：巩勋[1] 姜泉[1] 曹炜[1] 唐晓颇[1] 焦娟[1] 

机构地区：[1]中国中医科学院广安门医院,北京市西城区北线阁5号100053

出　　处：《中医杂志》2014年第14期1189-1192,共4页Journal of Traditional Chinese Medicine

基　　金："十二五"国家科技支撑计划资助项目(2013BAI02B00);国家自然科学基金资助项目(81273719;81373595)

摘　　要：类风湿关节炎(RA)引发的骨侵蚀是导致患者关节畸形和功能丧失的主要因素。受《黄帝内经》"肾主骨生髓"理论的影响,后世医家多从"肾"论治RA骨侵蚀。然而现代中医证候研究表明湿热瘀阻是活动期RA的主要病机,磁共振成像等现代影像学检测表明骨侵蚀在疾病早期就可发生。就此提出"非见骨损而独责之于肾",湿热瘀阻是引发RA活动期骨侵蚀的核心病机。Bone erosion is a major factor leading to joint deformity and loss of function in rheumatoid arthritis （RA） patients. Doctors later often treat bone erosion form the kidney as affected by the theory ＇ kidney governs the bones and engenders marrow＇ in Huangdi Neijing （Inner Canon of Huangdi）. Modern TCM syndrome research shows that damp-heat stasis obstruction is the main pathogenesis of active RA. Magnetic resonance imaging （MRI） and other modem imaging examinations have showed that bone erosion occurs in the early stage of RA. The core pathogenesis of bone erosion in active RA is damp-heat stasis obstruction.

关 键 词：类风湿关节炎 湿热瘀阻 骨侵蚀 

分 类 号：R259[医药卫生—中西医结合]