生长激素治疗特发性矮小疗效观察及分析  

Curative Effect Observation and Analysis of Growth Hormone Treatment for Idiopathic Short

作　　者：邓春晖[1] 张本金[1] 吕有道 雷克竞 姚毅[1] 

机构地区：[1]四川省达州市中心医院儿科,四川达州635000

出　　处：《现代生物医学进展》2014年第23期4516-4518,共3页Progress in Modern Biomedicine

摘　　要：目的:探究生长激素对特发性矮小(idiopathic short,ISS)的作用及临床疗效。方法:在我院临床接受ISS治疗的病患中,随机选取84例作为研究对象。按照随机分组法把其分为观察组(44例)和对照组(40例)。对照组进行常规治疗。观察组每日睡前注射生长激素0.16—0.20IU/kg。对比分析两组病患治疗后身高、身高标准差及生长速率情况。结果:对照组治疗后无明显增高现象,而观察组增高现象显著。差异均有统计学意义(均P<0.05)。观察组疗效优者占63.6%(28/44),优良率为95.5%(42/44),均明显高于对照组的35%(14/40),80%(32/40),差异均有统计学意义(均P<0.05)。结论:生长激素用于治疗ISS病患疗效显著,并能有效改善ISS病患身高、生长速率,安全性有保证,值得临床治疗广泛推荐。Objective： To explore the curative effect of growth hormone treatment for ISS. Methods： 84 cases of ISS treated in our hospital were randomly divided into two groups： observation group（44 cases） and control group（40 cases）. The control group received routine treatment while the observation group received daily injections of growth hormone 0.16-0.20 IU/kg. Standard deviation, growth rate and height of two groups were analyzed. Results： No significant height increase was observed in control group, however patients in observation group were heigher and the growth rate was significantly higher than that of control group（all P〈0.05）. Curative effect of observation group accounted for 63.6%（28/44） and fine rate was 95.5%（42/44）, which were notably higher than those in control group[respectively 35%（14/40）, 80%（32/40）]. The differences were statistically significant（all P〈0.05）. Conclusion： The growth hormone used in the treatment of patients with ISS presents distinct curative effect, and can effectively improve the ISS patient＇s height and growth rate. Its security can be guaranteed and is worthy to be widely recommended as a clinical therapy.

关 键 词：生长激素 特发性矮小 观察及分析 疗效 

分 类 号：R72[医药卫生—儿科]