老年主动脉瓣钙化与冠心病合并心律失常的相关性探讨  

Association between Senile Aortic Valve Calcification and Coronary Artery Disease Combined with Arrhythmia

作　　者：李建华[1] 晏沐阳[1] 周叶[1] 郑立通 赵军[1] 

机构地区：[1]解放军总医院老年心血管病研究所,北京100853

出　　处：《现代生物医学进展》2014年第23期4547-4549,4412,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81073093)

摘　　要：目的:探讨老年患者主动脉瓣钙化与冠心病合并心律失常的相关性。方法:纳入解放军总医院疑诊为冠心病的老年住院患者276例,行冠状动脉造影,同期行超声心动图和24 h动态心电图检查,详细记录患者病史。根据超声结果,将患者分成主动脉瓣钙化(AVC)组和非主动脉瓣钙化(NAVC)组,比较两组冠心病合并心律失常的检出率,评价老年患者主动脉瓣钙化对冠心病合并心律失常的预测价值。结果:AVC组和NAVC组的年龄、吸烟史、高血压史、糖尿病史存在显著性差异(P<0.05);AVC组冠心病的确诊率为93.7%,而NAVC组为80.6%,两组差异有统计学意义(P=0.002);AVC组冠心病合并心律失常检出率也显著性高于NAVC组(59.2%vs 35.1%,P=0.043)。结论:主动脉瓣钙化与冠心病合并心律失常密切相关,有望作为冠心病合并心律失常的高危患者有效的筛查指标。Objective： To investigate the correlation between aortic valve calcification and coronary artery disease combined with arrhythmia in elderly patients. Methods： 276 patients admitted to PLA general hospital and suspected coronary heart disease were selected and their detailed medical history were recorded after admission. They all underwent coronary angiography, echocardiography and 24 hour dynamic electrocardiogram at the same time. Patients were divided into aortic valve calcification（AVC） group and non-aortic valve calcification（NAVC） group according to the echocardiographic findings. The predictive value of senile aortic valve calcification was assessed though diagnosis rates of coronary heart disease combined with arrhythmia in AVC and NAVC groups.Results： There were significant differences in age, smoking history, history of hypertension, diabetes mellitus between AVCand NAVC groups（P〈0.05）. 93.7% and 80.6% patients were confirmed with coronary artery disease in AVC group and NAVC group, respectively.And the diagnosis rate was significantly different between the two groups（P=0.002）. Coronary heart disease combined with arrhythmia was more prevalent in AVC group（59.2% vs 35.1%, P=0.043）. Conclusion： AVC was closely correlated with coronary heart disease combined with arrhythmia. It could be used as an effective indicator for screening patients with coronary heart disease combined with arrhythmia.

关 键 词：老年 主动脉瓣钙化 冠心病 心律失常 

分 类 号：R541.4[医药卫生—心血管疾病]