5-取代吲哚化合物的合成研究  

Study on synthesis of 5-substituted indoles

作　　者：刘璐[1] 朱美霞[1] 辛春伟[1] 

机构地区：[1]天津理工大学化学化工学院,天津300384

出　　处：《天津理工大学学报》2014年第3期54-56,共3页Journal of Tianjin University of Technology

摘　　要：本文以吲哚和亚硫酸氢钠为原料,经吲哚啉中间体的步骤分别合成了5-溴吲哚、5-硝基吲哚与5-氨基吲哚,所合成的化合物利用核磁共振氢谱、红外光谱等进行了表征与确认,并对合成条件等进行了探讨.In this paper,substituted indoline were synthesized with indole and sodium bisulfite as raw materials. Through the＂indole-indoline-indole＂step,the target compound 5-bromo indole,5-nitro indole and 5-amino indole were gained. All synthesized compounds were confirmed by IR and 1HNMR. Besides,the synthesis conditions of intermediates were discussed.

关 键 词：吲哚 吲哚啉 5-取代吲哚 合成 

分 类 号：O626.13[理学—有机化学]