间苯三酚对小儿肠套叠水压灌肠复发率的影响  

Influence of m-trihydroxybenzene on the recurrence rate in children with intussusception hydrostatic enema

作　　者：轩爱军[1] 杨国强[2] 王立新[3] 刘玉敏[1] 李金英[1] 王海平[1] 朱秀玲[1] 唐靖[1] 王玉红[1] 

机构地区：[1]河北省玉田县医院B超室,064100 [2]河北省玉田县医院脑外科,064100 [3]河北省玉田县医院麻醉科,064100

出　　处：《中国基层医药》2014年第13期1945-1946,共2页Chinese Journal of Primary Medicine and Pharmacy

基　　金：河北省唐山市科技计划项目（121302043a）

摘　　要：目的 探讨间苯三酚在小儿肠套叠治疗中的应用价值,观察其疗效及安全性.方法 选择符合水压灌肠指征的肠套叠患儿共200例,采用随机数字表法分为两组,观察组100例在水压灌肠前15 min肌内注射间苯三酚（2 mg/kg）,再行水压灌肠复位.如复位成功,继续予以间苯三酚静脉滴注,每天1次.对照组100例,水压灌肠前使用阿托品（0.02 mg/kg）肌内注射,复位成功后未再继续使用解痉药物.比较两组患儿复位成功率、复位时间、复位后短期复发率及不良反应的差异.结果 观察组水压灌肠复位成功率为99％,显著高于对照组的87％（χ2=4.38,P＜0.05）;观察组复位成功时间为（7.56±2.54） min,显著短于对照组的（10.45±3.03）min,（t=-4.285,P＜0.05）.3d内观察组复发率为3％,显著低于对照组的13％ （χ2=2.79,P＜0.05）.观察组未发现明显不良反应.结论 间苯三酚在肠套叠患儿水压灌肠复位前后使用均是安全有效的,不但可以提高复位成功率,还可以明显降低复位后肠套叠的短期复发率.Objective To explore the application value of m-trihydroxybenzene in pediatric intussusception in the course of treatment,to observe its curative effect and safety.Methods 200 cases of enema intussusception were selected and randomly divided into two groups by the method of random number table.100 cases in the observation group were given m-trihydroxybenzene injection （2mg/kg） 15 minutes before hydrostatic enema,and reduction of hydrostatic enema.If reduction,continued to give benzene three phenol intravenous drip,once a day.100 cases in the control group used atropine（0.02mg/kg） intramuscular injection before hydrostatic enema,after successful reduction did not continue to use the spasmolytic drug.The success rate,short-term recurrence rate,reduction time and adverse reaction were compared between the two groups.Results The hydrostatic pressure enema reduction success rate of the observation group was 99%,which was significantly higher than 87% in the control group （χ2 =4.38,P 〈 0.05）.The reduction time of the observation group was （7.56 ± 2.54） min,which was significantly shorter than （10.45 ± 3.03） min of the control group （t =-4.285,P 〈 0.05）.The short-term recurrence rate in 3 days of the observation group was 3%,which was significantly lower than 13% in the control group （χ2 =2.79,P 〈0.05）.The observation group had no obvious adverse reaction.Conclusion m-Trihydroxybenzene in water enema intussusception reset before and after use is safe and effective,it can not only improve the success rate reduction,but also can significantly reduce the short-term recurrence of intestinal intussusception reduction rate.

关 键 词：间苯三酚 肠套叠 灌肠 超声检查 儿童 

分 类 号：R726.5[医药卫生—儿科]