补肾调经方药对肾虚型排卵障碍者治疗效果分析  

Effect of Bushen Tiaojing Decoction on nephrasthenia anovulatory infertility

作　　者：张金婷 杜淑英 王宁[3] 佟桂英 李巧凤 张国立 王尚明[3] 张树成[3] 

机构地区：[1]河北省承德县计划生育技术服务站,067400 [2]河南省新密市计划生育技术站 [3]国家人口计生委科学技术研究所

出　　处：《中国计划生育学杂志》2014年第7期460-464,共5页Chinese Journal of Family Planning

基　　金：国家重点基础研究发展计划(973计划;No.2010CB530403);国家自然科学基金(No.90409016)

摘　　要：目的：利用补肾调经中药治疗肾虚型排卵障碍评估中医＂从肾论治＂的效果。方法：采用自身对照和组间对照的方法,对167例排卵障碍性不孕妇女进行3个治疗周期和3个随访周期的观察,服用克罗米芬（西药组）55例,服用克罗米芬和补肾调经方药（中西药组）112例。结果：治疗后,肾虚型临床自觉症状表现总有效率中西药组（83.0%）高于西药组（43.6%）（P〈0.01）,总妊娠率中西药组（69.6%）高于西药组（41.8%）（P〈0.01）,周期妊娠率中西药组（23.0%）高于西药组（14.2%）（P〈0.05）,月经周期正常者中西药组（82.0%）高于西药组（71.1%）（P〈0.05）,排卵障碍表现者中西药组（25.9%）低于西药组（44.7%）（P〈0.01）,在LH-6～LH＋1子宫内膜发育中西药组均好于西药组（P〈0.05～0.01）。结论：补肾调经方药具有明确的调经、促排卵、健内膜作用,体现出中医药＂从肾论治＂思想的优势。Objective： To evaluate the effect of ＂treatment from kidney＂ by evaluating the effect of Bushen Tiaojing De- coction on nephrasthenia anovulatory infertility. Methods： By using a case-control and self-control study, 167 women with nephrasthenia anovulatory infertility were recruited for three treatment cycles and 3 follow-up cycles. Fifty-five women in the western medicine group took clomiphene citrate, and 112 women in the traditional Chinese and western medicine group were treated with clomiphene and Bushen Tiaojing recipe. Results： The degree of improvement of the clinical signs and symptoms in the traditional Chinese and western medicine group （83.0%） was significantly higher than that of the western medicine group （43.6%, P〈0.01）, the total pregnancy rate in the traditional Chinese and western medicine group （69.6%） was significantly higher than that of the western medicine group （41.8%, P〈 0.01）, the pregnancy rate per cycle （23.0%） in the traditional Chinese and western medicine group was significantly higher than that of the western medicine group （14.2%, P〈0.05）, the percentage of women with normal menstrual cycle （82.0 %） in the traditional Chinese and western medicine group was significantly higher than that of the western medicine group （71.1%, P〈0.05）, and the percentage those with ovulation disorder in the traditional Chinese and western medicine group （25.9 % ） was significantly lower than that of the western medicine group （44.7 %, P 〈0.01）, and the endometrial developments on the day of LH-6 to LH ＋ 1 in the traditional Chinese and western medicine group were significantly better than those of clomiphene group （P〈 0.05 to〈 0.01）. Conclusion： Bushen Tiaojing recipe plays a role in the physiological processes of menstruation, ovulation, endometrial rehabilitation, showing the advantage of ＂treatment from kidney＂ with traditional Chinese medicine.

关 键 词：排卵障碍性不孕症 排卵 补肾调经 不孕 补肾药 

分 类 号：R271.14[医药卫生—中医妇科学]