重症单核细胞增生型李斯特菌性脑干脑膜脑炎的特点及转归  

Characteristics and outcomes of brainstem meningoencephalitis caused by Listeria monocytogenes

作　　者：王萍[1] 魏红璐[1] 展群岭[2] 刘丽[2] 

机构地区：[1]重庆市第五人民医院检验科,400062 [2]重庆市第五人民医院神内科,400062

出　　处：《检验医学与临床》2014年第13期1776-1777,1780,共3页Laboratory Medicine and Clinic

摘　　要：目的总结重症单核细胞增生型李斯特菌性脑干脑膜脑炎的临床特点及治疗转归。方法根据临床症状、血液细菌培养和药敏试验结果,使用药物进行治疗,判断病情好转情况。结果血培养单核细胞增生型李斯特菌诊断为脑干脑膜脑炎(李斯特菌感染),使用青霉素联合氨基糖苷类药物治疗,病情好转出院。结论李斯特菌广泛存在于自然环境中,在免疫功能低下、老年人及糖尿糖病患者中,易引起中枢神经系统感染,在国内散发存在,病死率高,其确诊依赖于血液和脑脊液中检出单核细胞增生型李斯特菌。Objective To investigate the clinical features and outcome of brainstem meningoencephalitis caused by Listeria monocytogenes.Methods According to the clinical symptoms,blood bacterial culture and drug sensitivity test results,drugs were rationally used.Then,the disease condition was evaluated.Results The patient was diagnosed as brainstem encephalitis（Listeria monocytogenes）,based the blood culture result that Listeria monocytogenes was identified.Penicillin combined with aminoglycoside were used,and disease condition of the patient was improved and the patients was discharged.Conclusion Infection of central nervous system caused by Listeria,widely exist in the natural environment,could occur in peoples with low immune function,elderly subjects and diabetic patients,which might distributed exist in China,with high mortality,and its diagnosis should rely on the detection of Listeria monocytogenes in blood and cerebrospinal fluid.

关 键 词：单核细胞增生型李斯特菌 脑干脑膜脑炎 血培养 

分 类 号：R392.12[医药卫生—免疫学]