递进式策略治疗重症急性胰腺炎腹膜后感染回顾性研究  

Effect of step-up approach for retroperitoneal infection in patients with severe acute pancreatitis

作　　者：杭振宁[1] 冯向英[1] 王士祺[1] 李树钧[1] 王常青[1] 李芝帆[1] 吕艳香[1] 赵青川[1] 冯全新[1] 

机构地区：[1]第四军医大学西京消化病医院,西安710032

出　　处：《国际外科学杂志》2014年第6期386-389,共4页International Journal of Surgery

基　　金：国家自然科学基金（No.81270538;No.81170432）

摘　　要：目的 探讨递进式策略治疗重症急性胰腺炎腹膜后感染的疗效.方法 回顾性分析第四军医大学西京消化病医院治疗的94例重症急性胰腺炎腹膜后感染的患者资料,其中传统治疗方法38例,递进式策略治疗方法56例.比较两种治疗方法的并发症、住院天数、病死率情况.结果 与传统治疗方法相比,递进式策略治疗方法病死率（4/56 vs 8/38,P=0.047）、并发症（6/56 vs 12/38,P=0.029）均低于传统治疗组,新发糖尿病（10/56 vs 6/38,P=0.048）高于传统治疗组.结论 对于重症急性胰腺炎腹膜后感染递进式策略治疗是一种有效的方法,能明显减少手术并发症,提高治疗成功率.Objective To investigate the the efficacy of step-up approach for retroperitoneal infection in patients with severe acute pancreatitis.Methods The clinical data of 94 patients with SAP complicated with retroperitoneal infection who were admitted to our hospital were analyzed retrospectively.Patients were divided into 2 groups：routine therapy group（38 patients） and step-up approach group（56 patients）.The demographic characteristic,operation complications,hospital stays and mortality were compared between the two groups.Results Compared with routine therapy group,the step-up approach group had lower incidence of operation complications （6/56 vs 12/38,P =0.029） and mortality （4/56 vs 8/38,P =0.047）,higher rate of new-onset diabetes （10/56 vs 6/38,P =0.048）.Conclusions Compared with the routine therapy,the step-up approach reduces the incidence of postoperative complications and the rate of mortality.

关 键 词：胰腺炎 递进式策略治疗 腹膜后感染 手术后并发症 回顾性研究 

分 类 号：R657.51[医药卫生—外科学]