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作 者:张鑫[1] 佘丹阳[1] 刘又宁[1] 王睿[2] 邸秀珍[2] 梁蓓蓓[2] 王悦
机构地区:[1] 解放军总医院呼吸内科, 北京100853 [2]解放军总医院药物临床研究中心, 北京100853
出 处:《中华内科杂志》2014年第7期558-562,共5页Chinese Journal of Internal Medicine
基 金:国家科技部“十二五”重大专项滚动课题项目(2012ZX09303004-002)
摘 要:目的 从文献计量学角度对全球范围的细菌定量蛋白质组学研究的相关英文文献进行分析,旨在为细菌定量蛋白质组学的深入研究提供参考与借鉴.方法 英文文献检索Pubmed、Embase、科学引文索引(SCI)数据库中细菌定量蛋白质组学研究相关文献,英文数据库以“bacteria”和“quantitative proteomics”字段为检索词,截止日期均为2013年7月.利用EndNote X6软件进行分类整理,对纳入研究文献的发表年份、作者、发表期刊、研究机构、被引频次、文章类型等进行计量分析.结果 共纳入细菌定量蛋白质组学研究的英文文献932篇.第一篇于1999年报道,2012年达报道高峰(163篇).目前超过23个国家或地区有撰文报道,我国排名第4位.发表的文献类型均以论著为主,英文杂志发表细菌定量蛋白质组学研究的被引频次最高的英文文献:Silva JC,Gorenstein MV,Li GZ,et al.Absolute quantification of proteins by LCMSE:a virtue of parallel MS acquisition.Mol Cell Proteomics,2006,5:144-156.英文杂志发表细菌定量蛋白质组学研究篇数最多的作者及研究机构:Smith RD,Biological Sciences Division,Pac.Northwest National Laboratory.英文杂志发表细菌定量蛋白质组学研究最多的期刊:Proteomics.文献内容主要为运用定量蛋白质组学的方法,对细菌致病及耐药机制相关蛋白质的鉴定和分析、不同环境下细菌蛋白表达谱的变化等.结论 定量蛋白质组学日益受到全球范围的广泛关注,其在临床细菌学领域中的应用将会越来越广泛.Objective To analyze the worldwide advances on bacterial quantitative proteomics over the past fifteen years with bibliometric approach.Methods Literature retrieval was conducted throughout the databases of Pubmed,Embase and Science citation index (SCI),using "bacterium" and "quantitative proteomics" as the key words.The deadline is July 2013.We sorted and analyzed these articles with Endnote X6 from the aspects of published year,the first author,name of journal,published institution,cited frequency and publication type.Results 932 English articles were included in our research after deleting the duplicates.The first article on bacterial quantitative proteomics was reported in 1999.The maximal publications were 163 related articles in 2012.Up till July 2013,authors from more than 23 countries and regions have published articles in this field.China ranks the fourth.The main publication type is original articles.The most frequently cited article is entitled with Absolute quantification of proteins by LCMSE:a virtue of parallel MS acquisition by Silva JC,Gorenstein MV,Li GZ,et al in Mol Cell Proteomics 2006.The most productive author is Smith RD from Biological Sciences Division,Pac.Northwest National Laboratory.The top journal publishing bacterial quantitative proteomics is Proteomics.Conclusion More and more researchers pay attention to quantitative proteomics which will be widely used in bacteriology.
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