维吾尔族与汉族慢性阻塞性肺气肿患者凝血及纤溶指标对比分析  

Comparitive analysis on the coagulation and fibrinolysis indicator of Uighar patients and Hans patents with chronic obstructive pulmonary disease

作　　者：冯晖[1] 黄国虹[1] 祁晓婷[1] 卢佩佩[1] 

机构地区：[1]新疆维吾尔自治区人民医院临床检验中心,乌鲁木齐830011

出　　处：《检验医学与临床》2014年第A01期89-90,共2页Laboratory Medicine and Clinic

摘　　要：目的对比不同民族慢性阻塞性肺疾病（COPD）患者凝血及纤溶指标的差异。方法采集2012年1月至2013年12月收治于新疆维吾尔自治区人民医院呼吸科的122倒维吾尔族，160例汉族COPD患者及50例健康体检者的外周静脉血，测定各研究对象的凝血酶原时间（PT）、活化部分凝血酶原时间（APTT）、血浆纤维蛋白原（Fib）和D-二聚体（D-D）水平。结果cOPD患者与健康对照组相比，Fib与DD值明显增高，差异有统计学意义（P〈0．05），PT、APTT亦延长，但差异无统计学意义（P〉0．05）；维吾尔族与汉族COPD患者相比，Fib、D-D增高，PT、APTT延长，但差异均无统计学意义（P〉0．05）。结论不同民族COPD患者PT、APTT、Fib及D-D水平无明显差异，但是监测COPD患者体内的各凝血及纤溶指标的水平，可为预防、早期发现和及时治疗COPD提供参考。Objective To compare the difference of coagulation and fibrinolysis indicators in different-nation patients with chronic obstructive pulmonary disease（COPD）. Methods The peripheral blood samples were collected from 122 Uygur and 106 Han COPD patients and 50 health person,PT,APTT,Fib and D-D were detected. Results Compared with the health people, Fib and D-D of COPD patients were higher（P〈0.05）;PT, APTT were also longer,but the differences were not statistically significant. Uygur COPD patients had higher PT, APTT,Fib and DD than Han patients,but the differences had no statistical significance. Conclusion There was no statistical difference between Uygur and Han COPD patients, but the monitoring of coagulation and fibrinolysis indicators could provide reference to prevent,discovery early diagnosis and treat with COPD.

关 键 词：慢性阻塞性肺疾病 凝血 纤溶 

分 类 号：R692[医药卫生—泌尿科学]