2-取代苯并噁唑类化合物合成研究进展  

Progress in the Synthesis of 2-Substituted Benzoxazoles Derivatives

作　　者：肖立伟[1] 高红杰[1] 孔洁[1] 刘光仙[1] 彭晓霞[1] 王树军[1] 

机构地区：[1]廊坊师范学院化学与材料科学学院,廊坊065000

出　　处：《有机化学》2014年第6期1048-1060,共13页Chinese Journal of Organic Chemistry

基　　金：河北省自然科学基金(No.B2013408014);廊坊师范学院重点基金(No.LSZZ201302)资助项目~~

摘　　要：2-取代苯并噁唑类化合物在医药、农药以及配位催化等领域有广阔的应用前景,因而其合成方法备受关注.近年来,微波促进、水为介质、无溶剂合成、组合化学以及过渡金属催化等一系列高效、绿色的合成方法在2-取代苯并噁唑类化合物的合成中得到广泛的应用.按照不同的合成原料和合成方法进行分类,综述了近年来2-取代苯并噁唑类化合物合成研究的新进展.2-Substituted benzoxazole derivatives play important roles in pharmaceuticals, pesticide and coordination catalysis, so the synthetic methods for 2-substituted benzoxazoles have been attracted widely. Recently, a series of efficient green methods such as microwave irradiation, water as solvent, solvent-free, combinatorial chemistry and transition metal catalysis etc. have been used to synthesize 2-substituted benzoxazoles derivatives. Based on different starting materials and different methods, the recent advances in synthesis of 2-substituted benzoxazole are reviewed.

关 键 词：2-取代苯并噁唑 邻氨基苯酚 偶联反应 过渡金属催化 绿色化学 

分 类 号：O626.24[理学—有机化学]