右美托咪定对全麻腹腔镜手术术后CO_2蓄积患者复苏阶段的影响  

Effects of Dexmedetomidine to Anesthesia Laparoscopic Surgery on Postoperative Recovery Phase CO_2 Accumulation Patients

作　　者：邓方方[1] 吴昱[1] 

机构地区：[1]武汉市第一医院麻醉科,湖北武汉430030

出　　处：《江汉大学学报（自然科学版）》2014年第3期93-96,共4页Journal of Jianghan University：Natural Science Edition

摘　　要：目的观察右美托咪定对全麻腹腔镜手术术后CO2蓄积患者复苏阶段的影响。方法择期全麻行腹腔镜手术的患者,术毕前约40min测动脉血气,选取其中PaCO270～90mmHg,pH〈7.30的患者40例,随机分为对照组（N组）和右美托咪定组（D组）各20例。在手术结束前约30 min,N组患者给予0.9%氯化钠10mL静脉缓注,D组患者用右美托咪定配成4μg/mL浓度以0.8μg/kg剂量缓慢静注。记录两组患者在拔管时（T0）、拔管后5min（T1）、拔管后30min（T2）的心率、血压及Riker评分。两组患者从拔管开始到恢复满意可以送回病房所需时间（T3）。结果D组患者在T0、T1、T2时的心率、血压及Riker评分与N组患者比较差异均有统计学意义（P〈0.05）。两组患者从拔管开始到恢复满意可以送回病房所需时间的比较差异无统计学意义（P＆gt;0.05）。结论腹腔镜手术中,在CO2蓄积致高碳酸血症患者的麻醉复苏阶段,右美托咪定的作用是安全有效的。ObjectiveTo observe the effects of dexmedetomidine to anesthesia laparoscopic sur-gery on postoperative recovery phase CO2accumulation in patients.MethodsChose patients un-dergoing laparoscopic operation. Before the end of operation about 40 min measured arterial bloodgas. Selecting 40 cases of patients with PaCO270-90mmHg and pH7. 30. They were randomly divid-ed into a control group（group N）and dexmedetomidine group（group D）with 20 cases in each. Be-fore the end of operation about 30 min. N group were treated with 0. 9% sodium chloride 10 mL slowintravenous injection. D group were given the dexmedetomidine dubbed 4 μg/mL slow intravenouswith dose concentration 0.8 μg/kg. Recorded two groups of patients at extubation（T0）,5 min afterextubation（T1）,30 min after extubation（T2）of heart rate,blood pressure and Riker score. Twogroups of patients from extubation to can returned to the ward satisfaction time（T3）.Results Compared the group D with N,at T0,T1,T2 time,heart rate,blood pressure,and Riker scoreswere statistically significant（P 0. 05）. Comparison of the two groups was not statistically signifi-cant from extubation begin to restore satisfactory and could return to ward（P 0. 05）.ConclusionLaparoscopic surgery,CO2accumulation in patients with hypercapnia recovery phase of anes-thesia,given dexmedetomidine is safe and effective.

关 键 词：右美托咪定 腹腔镜手术 二氧化碳蓄积 

分 类 号：R971.2[医药卫生—药品] R614.2[医药卫生—药学]