大学生高血压前期与炎性细胞因子关系的研究  

Correlation analysis between prehypertension and inflammatory cytokines on university students

作　　者：刘萍[1,2] 罗海玲[1,2] 庄贤文[1,2] 

机构地区：[1]佛山市口腔医院 [2]佛山科学技术学院附属医院,广东佛山528000

出　　处：《现代预防医学》2014年第14期2585-2587,共3页Modern Preventive Medicine

基　　金：佛山市卫生局医学科研课题(2013178)

摘　　要：目的探讨大学生人群高血压前期与炎性细胞因子超敏C反应蛋白、白介素-6、肿瘤坏死因子的相关性。方法采取随机抽样方法 ,选择120名大学生,按照血压水平分为正常血压组(n=40)、高血压前期组(n=40)和高血压组(n=40),分别测定并比较血清超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)、肿瘤坏死因子(TNF-a)水平,分析3组上述指标之间的差异。结果与正常血压组比较,高血压前期组和高血压组的血清hs-CRP、IL-6及TNF-a水平显著升高(P<0.05);高血压组与高血压前期组相比hs-CRP、IL-6、TNF-a水平有所升高,但差异无统计意义(P>0.05)。结论大学生高血压前期患者血清中炎性细胞因水平明显升高,炎症反应可能与大学生高血压前期相关。Objective The study aimed to explore the correlation between prehypertension, high-sensitivity C-reactive protein, interleukin-6, and tumor necrosis factor-a on university students. Methods Random sampling method was used to select 120 university students, the subjects were divided into a normal group （n=40）, a prehypertension group （rt=40）, and a hypertension group （n=40） in accordance with blood pressure level. The levels of high-sensitivity C-reactive protein （hs-CRP）, interleukin-6 （IL-6）, and tumor necrosis factor-α （TNF-a） were detected respectively. Differences of the indicators of the three groups were analyzed. Results Compared with the normal group, the levels of hs-CRP, IL-6, and TNF-α in prehypertension group and hypertension group increased significantly （P〈0.05）. The levels of hs-CRP, IL-6, and TNF-α in hypertension group were higher than those in prehypertension group, there were no statistical significances （P〉0.05）. Conclusion The level of inflammatory cytokines in serum in prehypertension patients increases significantly, and the inflammatory reaction may relate to prehypertension on university students.

关 键 词：大学生 高血压前期 炎性因子 炎症 

分 类 号：R544.1[医药卫生—心血管疾病]