急性化脓性扁桃体炎卫分证外周血CD_3^+、CD_4^+和CD_8^+淋巴细胞亚群的变化及临床意义  

Changes and Clinical Significance of Peripheral CD_3^+,CD_4^+ and CD_8^+ Lymphocytes Subgroup in Acute Suppurative Tonsillitis with Wei Syndrome

作　　者：曾逸笛[1] 周小青[1] 刘建新[1] 洪净[1] 刘旺华[1] 

机构地区：[1]湖南中医药大学,湖南长沙410000

出　　处：《辽宁中医杂志》2014年第7期1407-1409,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：湖南省教育厅科研项目(08C621;10A093);湖南省高校创新平台开放基金项目(101C047)

摘　　要：目的:探讨急性化脓性扁桃体炎卫分证患者外周血中CD+3、CD+4和CD+8淋巴细胞亚群数目及比值变化。方法:对30例急性化脓性扁桃体炎卫分证患者和30例健康体检儿童用采用流式细胞技术检测外周血中CD+3、CD+4和CD+8淋巴细胞亚群的数目及比值。结果:与正常组比较,卫分证组CD+3、CD+4淋巴细胞亚群数目、CD+4/CD+3、CD+4/CD+8显著升高,CD+8/CD+3比值显著降低,差异有统计学意义(P<0.05)。结论:急性化脓性扁桃体炎卫分证可能与T淋巴细胞总数(CD+3)与T淋巴细胞CD+4亚群的数目均有明显增加有关。Objective：To investigate the clinical significance of CD3＋ , CD4＋ and CD8＋ lymphocytes subgroup＇s number and ratio change in peripheral blood in patients with acute suppurative tonsillitis of Wei syndrome. Methods：We detected peripheral blood CD3＋ , CD4＋ and CD8＋ lymphocytes subgroup number and ratio in 30 cases of acute suppurative tonsillitis of Wei syndrome patients and 30 cases bf healthy physical examination for children using flow cytometry technique to evaluate their relevance and clinical significance. 1results：Compared with normal control group, the number of CD3＋, CD4＋, CD4＋/CD3＋ and the CD4＋/CD8＋ ratio increased significantly, and the CD8＋/CD3＋ ratio decreased in Wei syndrome of acute suppurative tonsillitis （P 〈 0.05 ）. Conclusion： Results suggest that the Wei syndrome of acute suppurative tonsillitis is related to the significantly increased total number of T lymphocytes and the number of T lymphocytes CD; subgroup.

关 键 词：急性化脓性扁桃体炎 卫分证 T淋巴细胞 

分 类 号：R766.18[医药卫生—耳鼻咽喉科]