2011年滨州市手足口病重症病例流行病学及病原学分析  

Analysis on the epidemiological and etiological characteristics of severe cases of hand,foot and mouth disease in Binzhou City in 2011

作　　者：马长利[1] 颜伟[1] 吴杰[1] 张丽芳[1] 高艳玲[1] 

机构地区：[1]山东省滨州市疾病预防控制中心,山东滨州256600

出　　处：《实用预防医学》2014年第7期804-806,共3页Practical Preventive Medicine

摘　　要：目的总结分析2011年滨州市手足口病重症病例的流行病学及病原学特征,以制定针对性的防控措施,为预防手足口病重症病例的发生提供科学依据。方法回顾性调查分析2011年滨州市手足口病病例的流行病学特征和实验室检测结果;将手足口病病例按轻症病例和重症病例分成两组,对两组人群的性别、年龄、职业及病原学分布进行比较分析。结果 2011年共报告重症病例315例,较2010年(82例)上升284.15%,占手足口病病例总数(10 030例)的3.14%。重症病例发病高峰为4-7月,主要发生地区为滨城区、无棣县和阳信县,其中3岁以下男性散居儿童为主要发病人群,实验室检测结果主要以EV71型为主。轻症病例和重症病例相关因素比较结果显示,年龄、性别和病原学分布差异有统计学意义(P<0.05)。结论 2011年滨州市手足口病重症病例数显著增多,轻症病例和重症病例发生与年龄、性别和病原学特征有关。Objective To summarize and analyze the epidemiological and etiological characteristics of severe cases of hand, foot and mouth disease （I-{FMD） in Binzhou City in 2011 so as to develop targeted prevention and control measures and provide a sci- entific basis for prevention of severe HFMD cases. Methods We retrospectively surveyed and analyzed the epidemiological fea- tures and laboratory testing results of HFMD cases in Binzhou City in 2011. According to HFMD severity, all the cases were di- vided into mild HFMD group and severe HFMD group, and then the patients＇ gender, age, occupation and pathogen distribution were compared between the two groups. Results A total of 315 severe HFMD cases were reported in 2011, accounted for 3. 14 % of the total cases （315/10,030） and increased by 284.15 % compared with last year （n = 82）. The epidemic peak of severe HFMD cases was from April to July, and the epidemic areas focused on Bincheng District, Wudi County and Yangxin County. Most severe cases were scattered boys less than 3 years old, and laboratory testing results demonstrated enterovirus 71 （EV71） f. was the major causative pathogen of severe HFMD. The results of comparison of HFMD- related factors between mild cases and severe cases revealed that there were statistically significant differences in age, gender and pathogen distribution （P 〈 0.05）. Conclusions The severe cases of HFMD increased significantly in Binzhou City in 2011. The occurrence of mild and severe cases is related to age, gender and pathogenic characteristics.

关 键 词：手足口病 重症 分析 

分 类 号：R512.5[医药卫生—内科学]