类风湿性关节炎患者心肌酶检测的临床价值  

Clinical value of Myocardial Enzyme in patients with rheumatoid arthritis

作　　者：王建国[1] 王淑仙[1] 梁淑新[1] 朱姗姗[1] 李铁民[1] 

机构地区：[1]河北大学附属医院检验科,河北保定071000

出　　处：《医学研究与教育》2014年第3期14-16,共3页Medical Research and Education

摘　　要：目的探讨肌酸激酶(CK)和肌酸激酶同工酶(CK-MB)检测在类风湿关节炎(RA)患者合并心脏损害中的临床应用价值,为预测RA合并心脏损害及诊治提供参考依据。方法收集2010年至2013年间89例类风湿关节炎患者的血清,按有无心脏损害分为2组,对照组为健康体检者。分别检测3组患者血清中的心肌酶CK和CK-MB水平。结果 RA患者中心脏损害的发病率为37.1%,其血清CK和CK-MB水平明显高于其它2组血清水平,经统计学分析,其差异具有统计学意义(P<0.05);而RA无心脏损害组和健康对照组比较,经统计学分析,其差异无统计学意义(P>0.05)。结论检测RA患者血清心肌酶,在预测心脏损害方面具有重要价值,可为临床诊治提供重要参考依据,值得在临床推广应用。Objective To study the clinical application value of Myocardial Enzyme in the cardiac damage of patients with Rheumatoid Arthritis（RA） and provide a reference basis for the prediction of diagnosis and treatment of RA with cardiac damage. Methods The serum of 89 patients of RA between 2010 and 2013 were collected and detected the level of CK and CK-MB in serum with machine. They were divided into two groups, one group was patients of cardiac damage with RA and the other group was no cardiac damage. The healthy group is from the regular health check-up people. Results The incidence of RA with cardiac damage was 37.1%. The level of CK and CK-MB in cardiac damage with RA was signiifcantly higher than the other two groups, There was signiifcant differences in comparison between the group of cardiac damage with RA and the other two groups to the level of CK and CK-MB（P〈0.05）. There was no signiifcant differences in comparison between the group of no cardiac damage with RA and the healthy group to the level of CK and CK-MB （P〈0.05）. Conclusion There is important value in predicting cardiac damage to detect the level of Myocardial Enzyme in patients of RA and provide a reference basis for the prediction of diagnosis and treatment of RA with cardiac damage, which deserves further clinical application.

关 键 词：心肌酶 CK CK—MB 类风湿性关节炎 心脏损害 

分 类 号：R446[医药卫生—诊断学]