高压氧治疗对颅脑外伤患者认知功能障碍的影响  

Influence of hyperbaric oxygen therapy on cognitive impairments of patients with craniocerebral trauma

作　　者：梁叶[1] 黄波[1] 

机构地区：[1]广东高州市人民医院,高州525200

出　　处：《中国实用神经疾病杂志》2014年第13期9-11,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨高压氧治疗改善颅脑外伤患者认知功能障碍的临床疗效。方法回顾性分析2010-02—2012-08 68例颅脑外伤认知功能障碍患者的临床资料,随机分为2组,每组34例,对照组采用常规治疗,观察组在常规治疗基础上应用高压氧治疗,比较2组患者治疗后8周认知功能改善情况及临床疗效。结果治疗后8周,2组患者LOTCA总评分较治疗前明显增加(P<0.05),观察组积分大于对照组(t=3.0546,P=0.0032);观察组除"视运动组织"项外,各项目改善情况均优于对照组;观察组8月时治愈率和总有效率均优于对照组(χ2=4.8700、5.1000,P=0.0273、0.0239)。结论高压氧在颅脑外伤患者的治疗中有重要作用,尤其在改善认知功能障碍方面疗效显著。Objective To investigate the clinical effect of hyperbaric oxygen therapy on cognitive impairment of patients with craniocerebral trauma .Methods Clinical data of 68 patients with cognitive impairment after a craniocerebral trauma from February ,2010 to August ,2012 was retrospectively analyzed ,and randomly divided into two groups ,34 cases in each group . The control group was treated with conventional therapy ,the observation group was treated with hyperbaric oxygen based on the conventional therapy ,the clinical effect and improvement of cognitive function at 8th week after treatment were compared . Results The LOTCA total scores of patients in two groups after treatment for 8 weeks increased significantly than that before treatment （P〈0 .05） ,the LOTCA scores of the observation group was greater than that of the control group （t=3 .0546 ,P=0 .0032） ,the difference was statistically significant ;The improvement of all items of the observation group except the ＆quot;visual movement tissue＆quot;were superior to that of the control group ;The cure rate and the total effective rate of the observation group at 8th month were better than those of the control group （χ2 =4 .8700、5 .1000 ,P=0 .0273、0 .0239） .Conclusion Hyperbar-ic oxygen has an important role in the treatment of patients with craniocerebral trauma ,especially it has significant efficacy in improving cognitive dysfunction .

关 键 词：高压氧 颅脑外伤 认知功能障碍 

分 类 号：R651.15[医药卫生—外科学]