中度、重度慢性心力衰竭患者心功能改善对肾功能恢复的影响  

Effect of cardiac function improvement on the recovery of renal fuction in patients with moderate/severe chronic heart failure

作　　者：张春德[1] 陈斌[1] 张爱萍[1] 

机构地区：[1]安徽省淮南市第一人民医院心内科,安徽淮南232000

出　　处：《吉林医学》2014年第19期4222-4224,共3页Jilin Medical Journal

基　　金：淮南市科技项目[项目编号:2011A07402]

摘　　要：目的:探讨中度、重度慢性心力衰竭患者心功能改善对肾功能恢复的影响。方法:选取收治的60例中度、重度心力衰竭并发肾功能不全患者,对其进行心功能分级,Ⅲ、Ⅳ级患者分别分A,B组,分别观察比较其治疗前后血尿素氮(BUN)、血肌酐(Cr)、尿酸(UA)、胱抑素C(CysC)等各项指标的变化。结果:A组患者经抗心衰治疗后BUN、Cr、UA、CysC较治疗前明显降低,差异有统计学意义(P<0.01),B组患者经抗心衰治疗后Cr、UA、CysC较治疗前明显降低,差异有统计学意义(P<0.05)。结论:中度、重度心衰患者随着心功能改善,其肾功能有所恢复。Objective To explore effect of cardiac function improvement on the recovery of renal fuction in patients with moderate/severe chronic heart failure.Method 60 moderate/severe chronic heart failure patients with renal insufficiency were divided into two groups accroding to cardiac function （A group：New York heart function Ⅲ level,B group：New York heart function Ⅳ level） .The changes of blood urea nitrogen （BUN） ,serum creatinine （Cr） ,serum uric acid （UA） ,serum cystatin C （CysC） in subjects were observed respectively during hospitalisation.Results The BUN,serum Cr,serum UA,serum CysC levels in A group were lower after heart failure treatment.Every figures were significant statistic differences norm differences before and after the treatment （P〈0.01） The serum Cr,serum UA,serum CysC levels in A group were lower after heart failure treatment.Every figures were significant statistic differences before and after the treatment （P〈0.05） .Conclusion With the cardiac function improvement in patients with moderate/severe chronic heart failure,their renal function recovers partly.

关 键 词：心力衰竭 肾功能不全 血肌酐 胱抑素C 

分 类 号：R541.6[医药卫生—心血管疾病]