宫颈环形电切术治疗宫颈上皮内瘤变的应用研究  

Application of loop electrosurgical excision procedure for the treatment of cervical intraepithelial neoplasia

作　　者：张国琼[1] 

机构地区：[1]重庆市合川区人民医院,401520

出　　处：《检验医学与临床》2014年第14期1931-1932,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨宫颈环形电切术治疗宫颈上皮内瘤变的临床应用价值。方法选取合川区人民医院收治的宫颈上皮内瘤变患者80例作为研究对象,根据病理情况分为两组:观察组40例应用宫颈环形电切术进行治疗,对照组40例应用冷刀锥切术进行治疗。对比观察两组患者的临床疗效、术后并发症及预后复发情况。结果两组患者均顺利完成手术,无中转病例;与对照组比较,观察组患者的平均手术时间、创面愈合时间及术中出血量均明显减少,差异有统计学意义(P<0.01)。此外,术后根据患者个体情况分别完成6个月至2年的随访,与对照组相比,观察组术后治愈率显著升高,并发症发生率和复发率显著降低,各项指标差异均有统计学意义(P<0.05或P<0.01)。结论宫颈环形电切术疗效确切、安全性高,既能降低宫颈癌的发病率,又能保留患者子宫、满足其生育要求,值得临床进一步推广应用。Objective To analyze the clinical application value of loop electrosurgical excision procedure （LEEP） for the treatment of cervical intraepithelial neoplasia （CIN） .Methods A total of 80 patients with CIN ofⅠ - Ⅲ grade were divided into observation group （40 cases） ,receiving LEEP therapy ,and control group （40 cases） , receiving cold knife conization treatment .Clinical efficacy ,postoperative complications and recurrence rate were com-pared between the two groups .Results Surgery treatment was successfully completed in patients of both groups . Operative time ,bleeding volume and healing time in patients of observation group were all less than control group （P〈0 .05） .During the follow-up of 6 months to 2 years after surgery ;the cure rate of observation group was signifi-cantly higher than control group ,and the incidence rate of complications and recurrence rate were lower （P〈0 .05 or 〈0 .01） .Conclusion LEEP for the treatment of CIN might be efficient and safe ,which could reserve uterine and be worthy of further clinical application .

关 键 词：宫颈环形电切术 宫颈上皮内瘤变 冷刀锥切术 

分 类 号：R711.74[医药卫生—妇产科学]