降压治疗对高血压患者动态动脉硬化指数(AASI)的影响  

Antihypertensive Therapy Effect on Ambulatory Arterial Stiffness Index in Patients with Essential Hypertension

作　　者：李俊峰[1] 高金全[1] 王安伟[1] 张亚西[1] 张红[1] 刘瑶[1] 周瑜[1] 王莎莎[1] 张相[1] 

机构地区：[1]崇州市人民医院,四川崇州611330

出　　处：《四川医学》2014年第7期768-770,共3页Sichuan Medical Journal

基　　金：四川省卫生厅科研项目(编号:120459)

摘　　要：目的观察降压治疗对动态动脉硬化指数(ambulatory arterial stifness index,AASI)的影响,了解AASI在评估动脉硬化方面的价值。方法随访300例初治高血压患者,严格控制血压,并分别随访治疗0、1、3、6及12个月完成动态血压的检查;了解AASI的动态变化,观察AASI与降压治疗的相关性。结果严格降压治疗的原发性高血压患者,AASI呈逐步下降。结论动态动脉硬化指数(AASI)可作为高血压患者降压治疗效果的评估指标。Objective To observe the influence of antihypertensive therapy of ambulatory arterial stifness index（AASI） and understand the value of AASI in the evaluation of the hardening of the arteries. Methods 300 cases of initial treatment of patients with hypertension were followed up the ambulatory blood pressure ,witch were checked with strict control of blood pressure for 0, 1, 3, 6 and 12months,and to understand the dynamic change of AASI and to observe the correlation between AASI and the antihypertensive treatment. Results AASI showed a gradual declinthe with rigorous antihypertensive therapy in patients with essential hypertension（P 〈 0. 05）. Conclusion AASI can be used as the effectiveness of evaluation index with antihypertensive therapy in hypertensive patients.

关 键 词：原发性高血压 动态血压 动脉硬化 

分 类 号：R544.1[医药卫生—心血管疾病]