颈动脉彩色超声联合经颅多普勒检测早期评估糖耐量异常患者颈部及脑动脉血管的价值  

Carotid ultrasonography combined with transcranial Doppler to assess the early lesions of cerebral arteries in patients with impaired glucose tolerance

作　　者：张勇[1] 陈卓[1] 

机构地区：[1]绵竹市人民医院内一科,四川省618200

出　　处：《中华临床医师杂志（电子版）》2014年第12期34-37,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨联合颈动脉彩色超声及经颅多普勒的检测结果早期评估糖耐量异常患者颈部及脑动脉血管情况的临床价值。方法对40例糖耐量异常的患者使用颈动脉彩色超声(CDFI)测量颈动脉内膜-中层厚度,观察管腔是否有斑块、斑块性质、管腔是否狭窄闭塞、狭窄的程度及血流动力学变化。使用经颅多普勒(TCD)检查脑动脉收缩峰和舒张末期血流速度以及搏动指数,所有数据进行回顾性分析,并与40例健康对照组的检查结果进行比较。结果通过CDFI检查糖耐量异常组(IGT组)内中膜增厚人数及IMT值较糖耐量正常组(NGT组)均明显增高(P<0.01);通过TCD检查IGT组脑血管发生病变、血流速度及PI值均高于NGT组(P<0.05)。结论 CDFI联合TCD检查发现糖耐量异常患者早期已出现脑动脉的血流速度、搏动指数改变、颈动脉内中膜增厚,使用两种无创检查动态监测病变患者脑血管血流动力学变化,对于指导临床治疗、预防缺血性脑卒中的发生均具有重要的临床价值。Objective To observe the clinical value of Carotid ultrasonography（CDFI） combined with transcranial Doppler（TCD） to assess the early lesions of carotid and cerebral arteries in patients with impaired glucose tolerance（IGT）.Methods Carotid intima media thickness（IMT） of 40 patients with IGT were measured by CDFI, carotid plaque, luminal stenosis occlusion, the degree of stenosis and hemodynamic changes were observed. Cerebral artery Vp and Vd and PI were examined by TCD. All data were compared with the results of 40 peoples with normal glucose tolerance（NGT）.Results In IGT patients, carotid IMT were significantly higher than which of NGT peoples（P〈0.01）, cerebrovascular lesions, blood flow velocity and PI values were higher than which of NGT peoples （P〈0.05）.ConclusionsBy examination of CDFI combined with TCD, cerebral artery blood flow velocity, PI change, the carotid IMT, dynamic monitoring of cerebral blood flow changes could be observed in IGT patients with early vascular lesions, which had significant value for guiding clinical treatment, prevention of ischemic stroke.

关 键 词：颈动脉 脑动脉 超声检查 多普勒 彩色 超声检查 多普勒 经颅 糖耐量异常 

分 类 号：R445.1[医药卫生—影像医学与核医学] R587.1[医药卫生—诊断学]