他汀类药物在急性冠脉综合征住院患者应用现状调查  

Present situation investigation of use of statins therapy in patients hospitalized with acute coronary syndrome

作　　者：孙斌[1] 罗先润[1] 张辉[1] 李红满[1] 李朝辉[1] 朱中玉[2] 高传玉[2] 

机构地区：[1]武警河南总队医院,郑州450052 [2]河南省人民医院,河南省心血管流行病研究所

出　　处：《医药论坛杂志》2014年第6期9-12,共4页Journal of Medical Forum

摘　　要：目的调查他汀类药物在急性冠脉综合征患者住院期间的应用情况。方法调查2012年7月—2013年5月所有ACS患者452例,调查其他汀类药物的应用情况。结果 452例患者中有425例(94%)应用他汀类药物,最常用的他汀是阿托伐他汀,平均剂量16mg/d。15例(3.5%)患者应用强化剂量的他汀,96.5%患者接受标准剂量的他汀。27例没有应用他汀类药物患者中,7例有他汀禁忌症,20例没有禁忌症。住院期间应用他汀类药物与入院时LDL-C水平无关。结论在冠脉综合征住院患者中,接受他汀类药物的比例较高,但剂量不足,与指南推荐存在较大差距,需要加强对医生的教育。Objective To survey the use of statins therapy in patients hospitalized with acute coronary syndrome in clinical practices. Methods This cross -section survey in our hospital betweenj July 2012 and May 2013 was done. 452 patients admitted with acute coronary syndrome were investigated, all clinical data was collected. Statins use was recorded. Results Totally 425 patients received statins therapy in all 452 patients. Atrovastatin was most used, and its average dose was 16mg/d. 15 patients （3.5%） received intensive lower -lipid therapy, which 96. 5% of all patients received standard - dose lower - lipid therapy. 27 cases without application of statins in patients, 7 cases with statin contraindications, 20 cases no contraindications. Utilization of statins during hospitalization did not relate to admission LDL levels. Conclusion In patients admitted with ACS, most of the eligible patients were discharged on statins therapy, but their dosage weren＇ t enough. There was a big gap between guidelines recommendation and clinical practices. Need to strengthen the education of doctors.

关 键 词：他汀 急性冠脉综合征 调查 

分 类 号：R541.4[医药卫生—心血管疾病]