维C银翘片的红外光谱学研究  

Study on Infrared Spectrum of V_C Yinqiao Tablets

作　　者：戴传勇[1] 隆玉杰 银胜高[3] 辛宁[3] 黄云[3] 刘布鸣[4] 

机构地区：[1]广西农业职业技术学院,广西南宁530007 [2]广西邦尔药业有限公司,广西百色531500 [3]广西中医药大学,广西南宁530001 [4]广西中医药研究院,广西南宁530022

出　　处：《广西科学》2014年第3期275-278,共4页Guangxi Sciences

基　　金：广西科技厅项目(桂科攻11107010-3-6);广西中药质量标准研究重点实验室开放课题基金项目(GXGZZK201102)资助

摘　　要：【目的】探讨维C银翘片红外光谱学特性，为其质量控制提供参考。【方法】采用红外光谱法对广西盈康药业生产的10个不同批号维C银翘片进行检测，并以其平均图谱为标准图谱（即标准图谱为1）检测各样品的相似度。【结果】获得维C银翘片红外特征吸收峰；维C银翘片与维生素 C及与对乙酰氨基酚对照品三者的共有红外特征吸收峰；维生素C与对乙酰氨基酚的检识红外特征吸收峰；10批样品的相似度在0．9941～0．9993，拟定其阈值为0．9900。【结论】所建立的方法具有简便、快速、灵敏等特点，可为维 C银翘片的定性鉴别及其处方中的维生素C与对乙酰氨基酚检识提供参考。[Objective]The characteristics of infrared spectroscopy of vitamin C Yinqiao tablets were investigated in order to provide reference for its quality control.[Methods]Detection of 1 0 different batches of vitamin C Yinqiao tablets produced by Guangxi Yingkang Pharmaceutical Company using infrared spectroscopy,and its average spectrum was served as the standard atlas （i.e.standard atlas 1）to detect the similarity of each sample.[Results]The infrared character-istic absorption peaks were obtained from Vc Yinqiao tablets,which were characterized with the three common infrared characteristic absorption peaks among Vc Yinqiao tablets,Vc and acet-aminophen-control products,and for detecting both Vc and acetaminophen.The results showed that the similarity of 10 samples ranged from 0.9941 to 0.9993,formulated the threshold of 0. 9900.[Conclusion]This experiment method is simple,rapid,sensitive,which can provide refer-ence for qualitative identification of the Vc Yinqiao tablets and detection of Vc and acetaminophen in the prescription.

关 键 词：维C银翘片 维生素C 对乙酰氨基酚 红外光谱 

分 类 号：TQ460.7[化学工程—制药化工]