咽一方对小鼠耳肿胀及腹腔毛细血管通透性的影响  

Effect of Yanyifang on ear swelling and permeability of abdomen capillary in mice model

作　　者：欧阳芳[1] 薛敏菲[1] 吴声振[1] 

机构地区：[1]广东省佛山市中医院药剂科,528000

出　　处：《中国实用医药》2014年第19期6-7,共2页China Practical Medicine

基　　金：佛山市医学科学研究基金立项课题(项目编号:2013153)

摘　　要：目的研究咽一方对二甲苯所致小鼠耳肿胀及醋酸所致腹腔毛细血管通透性的影响。方法采用二甲苯致小鼠耳肿胀法观察咽一方对耳廓肿胀的抑制率,小鼠尾静脉注射伊文斯蓝,腹腔注射醋酸造模,测定吸光度。结果咽一方具有能显著抑制二甲苯致小鼠耳肿胀、醋酸致小鼠腹腔毛细血管通透性的作用。结论咽一方具有较强的抗炎作用。Objective To investigate the effect of Yanyifang on ear swelling induced by Xylene and permeability of abdomen capillary in mice model.MethodsXylene was used to induce ear swelling, and inhibition ratio of ear swelling was observed;Yiwensilan was injected into the vessel of mice tail, then acetic acid was injected into mice abdomen to cause inflammation and determine absorbency.ResultsYanyifang could significantly inhibit Xylene induced ear swelling and acetic acid induced permeability of abdomen capillary in mice model.ConclusionYanyifang has significantly action on anti-inflammatory.

关 键 词：咽一方 二甲苯 耳肿胀 醋酸 通透性 吸光度 小鼠 

分 类 号：R285.5[医药卫生—中药学]