不同用药方式治疗妊娠期高血压的疗效对比研究  

Efficacy on pregnancy-induced hypertension by different treatment methods

作　　者：谭艳丽[1] 杨健红[1] 

机构地区：[1]梧州市红十字会医院产科,广西梧州543002

出　　处：《中国医学前沿杂志（电子版）》2014年第6期85-87,共3页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

摘　　要：目的探讨硝苯地平联合硫酸镁、硝酸甘油联合硫酸镁治疗妊娠期高血压疾病的临床效果。方法 105例妊娠期高血压疾病患者根据入院时间被随机分为3组:A组(硫酸镁组),B组(硝苯地平联合硫酸镁组),C组(硝酸甘油联合硫酸镁组)。A组患者单纯使用硫酸镁静脉滴注降压,B组和C组患者在此基础上给予10 mg硝苯地平口服(每6小时1次)或用微量泵静脉注射硝酸甘油。分析3种不同用药方式的疗效。结果治疗后,3组患者血压均低于治疗前(P<0.05),且B组和C组降压效果优于A组(P<0.05);B组和C组患者自然分娩比率显著高于A组(P<0.05);B组和C组患者不良反应发生率和妊娠结局与A组患者比较差异具有显著性(P<0.05);而B组和C组间各监测指标比较无显著差异(P>0.05)。结论硝苯地平联合硫酸镁或硝酸甘油联合硫酸镁治疗妊娠期高血压疾病的临床效果均优于单独使用硫酸镁治疗,且二者均具有较好的安全性。Objective To discuss the clinical effect of nifedipine combined with Magnesium sulfate, Magnesium sulfate plus nitroglycerin treatment of pregnancy-induced hypertension. Method According to the date of admission, 105 cases of patients with pregnancy-induced hypertension were randomly divided into 3 groups, group A：Magnesium sulfate group, group B：nifedipine combined with Magnesium sulfate group, group C：nitroglycerin combined with Magnesium sulfate group. Group A were treated with Magnesium sulfate intravenous infusion, based on this group B and group C patients were given 10 mg oral （every 6 hours 1） or a micro pump intravenous nitroglycerin. The curative effects of 3 groups were analyzed. Result Compared with before treatment, 3 groups of pregnant women blood pressure were all decrease （P0.05）. Conclusion Nifedipine combined with Magnesium sulfate or nitroglycerin combined with Magnesium sulfate have more better clinical effects than that of Magnesium sulfate treatment of pregnancy induced hypertension, and both of the two have good safety.

关 键 词：妊娠 高血压 硝苯地平 硝酸甘油 硫酸镁 

分 类 号：R714.246[医药卫生—妇产科学]