硫酸氢钠-硫酸催化合成水杨酸苯酯的研究  

Study on synthtsis of phenyl salicylate catalyzed by sodium bisulfat-concentrated suifuric acid

作　　者：冯子娟 黄海明[1] 袁旭宏[2] 叶余原[1] 陈红[1] 尤玉静[1] 熊双喜[1] 

机构地区：[1]台州学院医药化工学院,浙江台州38000 [2]台州职业技术学院生化系,浙江台州38000

出　　处：《化学工程师》2014年第7期16-18,共3页Chemical Engineer

基　　金：台卅学院培育基金(2013py26)

摘　　要：用NaHSO4与H2SO4相混合共同催化水杨酸与苯酚进行酯化反应,制成了水杨酸苯酯。方法相当简便,效果较好。本实验研究了多种影响酯化率的反应因素与催化剂的反复使用次数,得出结论如下:当水杨酸、苯酚和NaHSO4的物质的量比为1∶1.3∶0.75,H2SO46D,回流分水150min,酯收率达86.7%。The sodium bisulfate and the combination of concentrated sulfuric acid and salicylic acid catalyzed esterification of phenol, phenyl salicylate was synthesized.Simple and effective. This experiment studied the effects of yield response factors and reuse of the catalyst performance, conclusions：When salicylic acid, phenol and sodium hydrogen sulfate molar ratio of 1：1.3：0.75, 6drops of concentrated sulfuric acid, Refluxing 150 m in, ester yield of 86.7%.

关 键 词：水杨酸苯酯 合成 硫酸氢钠 硫酸 催化 

分 类 号：TQ245.4[化学工程—有机化工]