血三七胶囊的质量控制研究  

Study on the quality control for Xuesanqi capsules

作　　者：向梅先[1] 苏汉文[2] 刘环香[2] 

机构地区：[1]中南民族大学药学院,湖北武汉430074 [2]武汉大学人民医院,湖北武汉430060

出　　处：《中国医院药学杂志》2014年第14期1148-1150,共3页Chinese Journal of Hospital Pharmacy

基　　金：国家自然科学基金项目(编号:31200264);武汉市科技攻关项目(编号:201260523189)

摘　　要：目的：建立血三七胶囊质量控制标准。方法：采用薄层色谱法进行定性鉴别，用高效液相色谱法（HPLC）法对血三七胶囊中大黄素进行含量测定。结果：薄层定性条件适合，斑点清晰，HPLC定量方法分离效果好，线性范围0．14～1．12μg（r=0．9994），平均回收率99．84％，RSD=0．43％。结论：本法简便、快速、准确，可作为血三七胶囊质量控制方法。OBJECTIVE To establish a quality standard for Xuesanqi capsules. METHODS TLC was used to identify emodin quality in Xuesanqi capsules. The quantitative analysis method of emodin for Xuesanqi capsules was determined by HPLC. RENULTS Conditions of qualitative identity by TLC were suitable. The results of quantitative analysis by HPLC were good. The linear range was between 0. 14 g to 1. 12 g （R = 0. 999 4）, the recovery of average was 99. 84%, RSD= 0. 43%. CONCLUSION The method is simple, sensitive and suitable for the quality control of Xuesanqi capsules.

关 键 词：血三七胶囊 质量标准 大黄素 

分 类 号：R944[医药卫生—药剂学]