机械通气肺损伤机制及防治新进展  

The Mechanism and New Progress of Prevention and Treatment in Mechanical Ventilation Lung Injury

作　　者：黄涛 高巨 徐军美 

机构地区：[1]扬州大学临床医学院麻醉科,江苏扬州225001 [2]中南大学湘雅医学院第二附属医院麻醉科,长沙410011

出　　处：《医学综述》2014年第12期2173-2175,共3页Medical Recapitulate

基　　金：国家自然科学基金(81171838);江苏省医学重点人才项目(RC2011041);扬州市社会发展攻关项目(YZ2010085)

摘　　要：机械通气在危重病患者的救治过程中起着非常重要的作用,然而使用不当,可以诱发或者加重肺损伤,即呼吸机相关性肺损伤(VILI)。随着对VILI发病机制的不断探索,并采取了一些相应的防治措施,例如保护性通气模式、生物防治等,能在一定程度上减轻VILI的损伤程度。该文就机械通气肺损伤的发生机制、防治策略等方面的研究新进展予以综述。Mechanical ventilations saves lives of many critically ill patients. But inappropriate use of mechanical ventilation will induce or aggravate lung injury （ventilator-induced lung injury, VILI）. Over the years, researchers are exploring the pathogenesis of VILI in different aspects and taking corresponding preven- tion and treatment measures, such as protective ventilation mode, biological control and so on, which are helpful to mitigate the severity of VILI to a certain degree. Here is to make a review of the new progress of the mechanism and prevention and treatment in VILI.

关 键 词：机械通气相关肺损伤 肺保护性通气 生物伤 

分 类 号：R164.2[医药卫生—公共卫生与预防医学]