腹腔镜子宫肌瘤剔除术联合抗生素治疗对围术期患者体内炎性因子的影响  

The Influence of Laparoscopic Myomectomy Combined with Antibiotic Therapy on Inflammatory Factors in Perioperative Uterine Fibroids Patients

作　　者：周利敏[1] 

机构地区：[1]湖北省妇幼保健院妇科,武汉430070

出　　处：《医学综述》2014年第13期2451-2452,共2页Medical Recapitulate

摘　　要：目的探讨腹腔镜子宫肌瘤剔除术联合抗生素治疗对围术期患者体内炎性因子的影响。方法选取2013年1月至7月湖北省妇幼保健院妇科收治的子宫肌瘤患者60例,依据治疗方式不同分为两组:30例接受开腹手术联合抗生素治疗(开腹组)和30例接受腹腔镜手术联合抗生素治疗(腹腔镜组)。比较两组手术前后白细胞介素1β(IL-1β)、IL-8β、C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)及干扰素γ(IFN-γ)的水平。结果术前两组IL-1β、IL-8β、CRP、TNF-α及IFN-γ比较未见明显差异,术后1 d、术后3 d及术后7 d腹腔镜组的IL-1β、IL-8β、CRP、TNF-α及IFN-γ水平均显著低于开腹组(P<0.05)。结论腹腔镜子宫肌瘤剔除术联合抗生素治疗子宫肌瘤对患者体内炎性因子的影响较小。Objective To investigate the influence of laparoscopic myomeetomy combined with antibiotie therapy on inflammatory factor in perioperative patients. Methods Perioperative inflammtory factor,interleukin-1β （ IL-1β）, interleukin-8β （ IL-8 β ）, C-reactive protein （CRP）, tumor necrosis faetor-α （ TNF-α ） and interferon-γ（IFN-γ） levels were compared between 30 uterus lciomyoma eases who received the treatment of open operation ith antibiotic therapy （ open group） and 30 eases who received the treatment of laparoseopic myomeotomy with antibiotic therapy （laparoscopie group） during Jan. 2013 and Jul. 2013. Results Preoperative IL-1β,IL-1β,CRP,TNF-α and IFN-γ, had no obvious difference between the two groups, while IL-1 β, IL-1β, CRP, TNF-α and IFN-γ in the laparoseopie group was significantly lower than that in open group 1 day,3 days and 7 days after treatment. Conclusion The treatment of laparoscopic myomeotomy combined with antibiotic therapy has less impact on inflammatory factors in the uterine fibroids patients.

关 键 词：腹腔镜检查 子宫肿瘤 抗生素类 抗肿瘤 手术期间 细胞因子类 

分 类 号：R713[医药卫生—妇产科学]