清新地区短暂性脑缺血发作患者年龄对后继脑梗死的影响  

Impact of Age of Patients with Transient Ischemic Attack on Subsequent Infarction in Qingxin Area

作　　者：马康胜 吴碧娟 

机构地区：[1]广东省清远市清新区人民医院,广东清远511800

出　　处：《临床医学工程》2014年第7期941-942,共2页Clinical Medicine & Engineering

摘　　要：目的探讨清新地区TIA患者发生后继脑梗死与患者年龄的相关性。方法调取2012年1月至2013年12月间确诊的脑梗死病例资料118例,根据患者脑梗死前1周内是否发生TIA分为TIA组和对照组,两组根据年龄再分为<65岁和≥65岁组,比较患者神经功能缺损MESSS评分和日常生活能力Barthel评分。结果年龄<65岁的TIA组患者MESSS评分极显著低于对照组,Barthel评分极显著高于对照组(P<0.01);年龄≥65岁患者两组MESSS和Barthel评分比较无统计学差异(P>0.05)。结论 TIA的缺血耐受作用与患者年龄具有一定相关性,低于65岁患者TIA发生后1周内出现后继脑梗死,TIA可产生较强的神经保护作用,缓解生活能力的下降程度,而年龄超过65岁患者的TIA神经功能保护作用则明显减弱。Objective To investigate the correlation between subsequent infarction of patients with transient ischemic attack （TIA） and their age. Methods The clinical data of 118 patients with cerebral infarction from January 2012 to December 2013 were analyzed retrospectively. All cases were divided into TIA group and control group, and each group was divided into two groups according to age： 〈 65 years old and I〉 65 years old. The neurological deficit score （MESSS） and activities of daily living score （Barthel score） were compared. Results For cases 〈 65 years old, the MESSS score of TIA group was significantly lower than that of control group, and the Barthel was significantly higher than that of control group （P 〈0.01）. For cases 〉~65 years old, there were no statistical differences in MESSS score and Barthel score between TIA group and control group （P 〉0.05）. Conclusions The ischemic tolerance of TIA is related to patients＇ age, for patients less than 65 years old, subsequent infarction occurs within 1 week after TIA. TIA can produce a strong neuroprotective effect, and alleviate the decline of ability of living, but for patients over 65 years old, the neuroprotective effect of TIA reduces significantly.

关 键 词：短暂性脑缺血 后继脑梗死 年龄因素 相关性 

分 类 号：R195.4[医药卫生—卫生统计学]