新西兰兔脑电的生物学特性  

Biological characteristics of rabbit electroencephalography(EEG)

作　　者：恽时锋[1] 方天[1] 董敏[1] 赵志刚[1] 梁磊[1] 许龙祥[1] 陈莉[1] 刘彪[1] 吴正林[1] 田小芸[1] 周森妹[1] 

机构地区：[1]南京军区南京总医院比较医学科,全国科普教育基地,南京210002

出　　处：《中国比较医学杂志》2014年第6期40-44,62,共6页Chinese Journal of Comparative Medicine

摘　　要：目的研究封闭群新西兰白兔颅外头皮脑电图（EEG）及颅内大脑皮质脑电图（ECoG）。方法对封闭群新西兰白兔进行颅外头皮脑电图及颅内大脑皮质脑电图描记,并比较、观察和分析两种方法的描记结果。结果 EEG以9~12c/s的α波及16~20 c/s的β波为基本节律,波幅为30~100μV;ECoG则以10~12c/s的α波及16~20 c/s的β波为基本节律,波幅为200~300μV;麻醉能使脑电活动减弱,脑组织缺氧,麻醉后ECoG以δ及θ慢波为主。结论 EEG测定方法简单,操作简便,家兔无需麻醉,无创伤,所描记的脑电波形与ECoG高度一致,可以替代传统的ECoG进行神经系统功能的研究。Objective To study the extracranial scalp electroencephalography（EEG） and intracranial electrocorticography（ECoG） of closed colony New Zealand white rabbits. Methods To record the extracranial scalp EEG and intracranial ECoG of closed colony New Zealand white rabbits,and to compare and analyze the results of those two scanning methods. Results EEG was characteristic of 9-12 c /s α wave and 16-20 c /s β wave with an amplitude of 30-100μV as the basic rhythm. ECoG showed 10-12 c/s α wave and 16-20 c/s β wave with an amplitude of 200-300 μV as the basic rhythm. Anesthesia could attenuate the electrocerebral activity,cause brain tissue hypoxia,and induce δ wave and slow θ wave in ECoG. Conclusions EEG method is a simple,non-invasive and convenient operation,and can be made in rabbits without anesthesia. The recorded EEG waveform is highly consistent with that of ECoG,and may be used as an alternative to the traditional ECoG in neurofunctional studies.

关 键 词：新西兰白兔 体温 合格率 脑 头皮 脑电图 

分 类 号：R33[医药卫生—人体生理学]