麻醉手术期间影响脉搏波传导时间的相关因素  

The factors affecting pulse transit time during anesthesia

作　　者：蒋宇智[1] 孙杰[1] 曹小飞[1] 魏国华[1] 丁正年[1] 

机构地区：[1]南京医科大学第一附属医院麻醉科,南京市210029

出　　处：《临床麻醉学杂志》2014年第7期682-685,共4页Journal of Clinical Anesthesiology

摘　　要：目的探讨麻醉手术期间影响脉搏波传导时间(PTT)的相关因素。方法随机选择全麻胃肠道择期手术患者60例,常规全静脉复合麻醉,记录患者麻醉诱导前后、术中血管活性药给药前后的PTT、BP、HR。结果与给药前比较,给予阿托品、麻黄碱后HR明显增快,SBP、DBP明显升高,PTT明显缩短(P<0.01);给予尼卡地平后HR明显增快,SBP、DBP明显降低,PTT明显延长(P<0.01);给予去氧肾上腺素后HR明显减慢,SBP、DBP明显升高,PTT明显缩短(P<0.01)。诱导前后,SBP与PTT呈明显负相关(P<0.01),而DBP与PTT相关性较差;HR与PTT相关性不明显。给予阿托品、尼卡地平、麻黄碱和去氧肾上腺素前后,SBP与PTT分别呈明显负相关(P<0.01)。结论 PTT与SBP呈显著负相关。Objective To investigate the factors affecting pulse transit time during anesthesia. Methods Sixty cases of gastrointestinal surgery under general anesthesia were investigated.The pulse transit time （PTT）,BP and HR were measured at the time before and after intravenous anes-thesia induction,and at the time before and after the injection of vasoactive drugs,respectively. Results Compared to at the time before injection,HR,SBP and DBP increased significantly,and PTT decreased significantly （P 〈0.01 ）at the time after injection of atropine and ephedrine.Com-pared to at the time before injection,HR and PTT increased significantly,while SBP and DBP de-creased significantly （P 〈 0.01 ）at the time after injection of nicardipine.While HR and PTT de-creased significantly,and SBP,DBP increased significantly （P 〈0.01 ）with the injection of pheny-lephrine.Obvious negative correlation between SBP and PTT was observed before and after induc-tion;meanwhile,only weak correlation between DBP and PTT was observed,and no obvious correla-tion between HR and PTT was detected.SBP and PTT were well negatively correlated with the injec-tion of atropine,ephedrine,nicardipine or phenylephrine.Conclusion All the PTT changes during anesthesia were found to be negatively correlated with the systolic blood pressure.

关 键 词：脉搏波传导时间 血管活性药物 收缩压 

分 类 号：R614[医药卫生—麻醉学]