大骨瓣开颅术治疗110例外伤后急性弥漫性脑肿胀的疗效分析  

Analysis of large bone flap craniotomy for 110 cases of posttraumatic acute diffuse brain swelling

作　　者：郭斯檾[1] 

机构地区：[1]广州中医药大学附属佛山中医院,广东广州528000

出　　处：《中医临床研究》2014年第12期49-50,52,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的：探讨大骨瓣开颅术治疗外伤后急性弥漫性脑肿胀的临床疗效。方法：选取我院在2010年3月～2013年3月收治的110例外伤后急性弥漫性脑肿胀患者作为研究对象。根据治疗方法的不同，将110例患者分为研究组和对照组，每组55例，研究组患者行大骨瓣开颅术进行治疗，对照组患者行常规开颅手术，对两组患者的治疗效果进行比较分析。结果：经治疗，研究组患者恢复良好率为42.3%（26/55），显著高于对照组21.8%（12/55），差异具有统计学意义（P〈0.05）；研究组的死亡率为18.2%，对照组为41.8%，研究组显著低于对照组，差异具有统计学意义（P〈0.05）；研究组患者的治疗有效率为76.4%，对照组为52.7%，组间比较，差异具有统计学意义（P〈0.05）。结论：对于术后急性弥漫性脑肿胀患者行大骨瓣开颅术，可充分降低颅内压，使继发性颅脑损伤程度减轻，从而有效改善患者预后，降低死亡率。Objective：To investigate the clinical efficacy of large craniotomy on posttraumatic acute diffuse brain swelling. Methods：110 cases of posttraum atic acute diffuse brain sw elling in our hospital from March 2010 to March 2013 were selected as research objects. According to different treatments, 110 patients were divided into a research group and a control group, 55 cases in each group. Patients in the treatment group were treated with craniotomy , while patients in the control group treated with conventional cr aniotomy and the therapeutic effects of the two groups were compared. Results：After treatment , the good recovery rate of the research group was 42.3%（26/55 ） , sign ificantly h igher than 21.8%（12/55） of the control group, statistically significant dif ference（P〈0.05）. T he mortality of t he research group was 18.2%, 41.8%in the control group , and the research group was significantly lower than that of the control group , P〈0.05;the effective rate of the research study group 76.4%, 52.7%in the control group,statistically significant difference（P〈0.05）. Compared the two groups, the difference was statistically s ignificant （ P〈0.05 ）.Conclusion：Large cran iotomy on posttraumatic acute diffuse brain swelling can canfully reduce in tracranial pr essure and the secondary br ain in jury , thereby effectively improve patient outcomes and reduce mortality.

关 键 词：急性弥漫性脑肿胀 大骨瓣开颅术 外伤 颅内压 

分 类 号：R651.15[医药卫生—外科学]