晚期孕妇生殖道感染无乳链球菌与新生儿感染的相关性研究  

The correlation between puerperal reproductive tract infection with Streptococcus agalacticus and neonatal infection

作　　者：胡利春[1] 邹洁洁 陈海燕[1] 

机构地区：[1]慈溪市妇幼保健院检验科,浙江慈溪315300

出　　处：《中国微生态学杂志》2014年第7期836-838,共3页Chinese Journal of Microecology

摘　　要：目的探讨妊娠晚期妇女生殖道感染无乳链球菌(GBS)与新生儿感染的关系。方法在慈溪市妇幼保健院1 192例胎膜早破妊娠晚期妇女进行宫颈分泌物培养,同时对其分娩的1 196个新生儿进行鼻咽分泌物培养作为观察组,同时选择同期无胎膜早破的妊娠晚期妇女500例作为对照组进行比较。观察胎膜早破合并GBS阳性妊娠晚期妇女与新生儿感染的相关性。结果观察组分离无乳链球菌比例为16.1%(192/1192),对照组分离无乳链球菌比例为6.0%(30/500),两组比较无乳链球菌感染与胎膜早破差异有统计学意义(P<0.05)。早破合并GBS阳性的妊娠晚期妇女新生儿感染率与破膜时间和分娩产程有关,破膜时间<24 h与>24 h的妊娠晚期妇女,其新生儿感染率与破膜时间成正比,产程<24 h的妊娠晚期妇女新生儿感染率明显低于24 h以上的妊娠晚期妇女。结论妊娠晚期妇女无乳链球菌感染与胎膜早破有关,从而引起新生儿感染,为了早期预防新生儿感染,应对GBS阳性的妊娠晚期妇女及时治疗,并严格控制早破时间和缩短分娩产程。Objective To investigate the relationship between the puerperal reproductive tract infection with Strep- tococcus agalacticus （GBS） and neonatal infections. Methods We set up two experiment groups, observation group and control group. The relationship between Puerperal reproductive tract infection with Streptococcus agalacticus and Neonatal infections was observed. Results The isolation rate of Streptococcus agalacticus in the observation group was 16.1% （192/1192）, while that of control group was 6.0% （30/500）. The differences in Strepto- coccus agalacticus infection and premature rupture of membranes between the two groups were statistically significant （ P 〈 0.05 ）. In GBS positive premature rupture of membrane cases, neonatal infections were associated with rupture time and delivery process. In cases with rupture time over or below 24 hours, the neonatal infection rate was proportional to the time of rupture. The neonatal infection rate in cases with labor process of below 24 hours was significantly lower than that of 24 hours or more. Conclusion Streptococcus agalacticus infection can lead to premature rupture of membranes and cause neonatal infection. For the purpose of early prevention of neonatal infection, late term pregnant women with positive GBS results should be treated in time, the premature rupture should be strictly controlled and labor process be shortened.

关 键 词：妊娠晚期妇女 新生儿 感染 无乳链球菌 

分 类 号：R714.2[医药卫生—妇产科学]