由1-萘乙腈制备1-萘乙酸乙酯合成研究  

Synthesis of Ethyl 1-Naphthylacetate from 1-Naphthyl Acetonitrile

作　　者：杨杰[1] 吕宏飞[1] 李猛[1] 徐虹[1] 王艳华[1] 李淑辉[1] 梅立鑫 

机构地区：[1]黑龙江省科学院石油化学研究院,黑龙江哈尔滨150040

出　　处：《化学与粘合》2014年第4期277-278,281,共3页Chemistry and Adhesion

基　　金：黑龙江省科学院春苗资助专项

摘　　要：通过1-萘乙腈在酸催化下合成1-萘乙酸,进而与乙醇发生酯化反应合成1-萘乙酸乙酯。考察了不同酸浓度及酸体系对1-萘乙腈水解反应的影响,确定混合酸H2SO4∶HOAc∶H2O=1∶1∶1(V%)为最佳酸催化体系;同时考察了酸醇质量体积比对酯化反应的影响,确定了酸醇质量体积比为1∶3;并对产物进行了红外结构分析,确定合成的为目标化合物。The 1-naphthylacetic acid is synthesized from 1-naphthyl acetonitrile with the catalysis of acid, and then the esterification reaction takes place between the 1-naphthylacetic acid and ethanol to prepare ethyl 1-naphthylacetate. The effects of different concentrations of acid and various kinds of acid system on the hydrolysis of 1-naphthylacetonitrile are investigated, and the optimal acid system is confirmed as follows： H2SO,： HOAc：H2O=1：1：1 （volume ratio）. The influence of mass volume ratio of acid to alcohol on the esterification is also researched and determined which is 1：3; the product is confirmed to be the target compound through IR spectrum.

关 键 词：1-萘乙酸 水解 1-萘乙酸乙酯 

分 类 号：TQ452.1[化学工程—农药化工]