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机构地区:[1]北京市房山区第一医院药剂科,北京102400 [2]首都医科大学附属北京天坛医院药剂科,北京100050
出 处:《药品评价》2014年第10期39-41,共3页Drug Evaluation
摘 要:患者因脑积水行脑室外引流术后出现颅内感染和肺部感染。抗感染治疗治疗过程中,患者出现转氨酶升高的情况。加用保肝药物并停用相关药物后,患者转氨酶数值下降明显。经过多次调整抗感染治疗方案,患者颅内感染和肺部感染均被控制。但治疗过程中,在药物选择和用法方面仍需改进,还应密切观察患者肝肾功能变化情况,及时停用相关药物,确保患者用药安全。A patient was given externalventricular drainage surgery for hydrocephalus, and thereafter the patient got intracranial and pulmonary infection. During the process of anti-infection treatment, increase of hepatic transaminases appeared.Hepatic protective drugs were given and hepatotoxic drugs were stopped. Then blood transaminase decreased. The anti-infection treatment was adjusted for several times, and the intracranial and pulmonary infections in the patient were controlled. Still, it was necessary to improve the drug selection and usage in the treatment, and we should closely observe the changes of the liver and kidney function, stop related drugs in time if hepatic or nephral toxicity happened in order to ensure patient safety.
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